Sunday, July 5, 2009

Treatment Options for Pleural Mesothelioma

Mesothelioma is a deadly cancer that is directly attributed to asbestos exposure. There are three forms of mesothelioma. These forms are pleural mesothelioma, peritoneal mesothelioma and pericardial mesothelioma. This devastating cancer attacks the mesothelium, or the protective lining of the lungs, abdominal cavity, and heart respectively.

Of the three forms of mesothelioma, pleural mesothelioma is the most common. When asbestos is manufactured, mined or disturbed asbestos fibers are released into the air. Those working with or around asbestos inhale and ingest these fine particles. Over an extended period of time, mesothelioma can take 20 to 60 years to manifest, these asbestos particles can cause normal pleura in the lining of the chest to become abnormal, causing pleural mesothelioma.

Some of the most common symptoms of pleural mesothelioma are persistent cough, shortness of breath, bloody sputum, weight loss, fever, swelling of the face and neck, raspy voice and trouble swallowing. Due to the symptoms of pleural mesothelioma mimicking symptoms of other conditions it may go undiagnosed when the need to start mesothelioma treatment immediately is vital.

After a definitive diagnosis of pleural mesothelioma has been established there are several mesothelioma treatment options that can be undertaken. The type of mesothelioma treatment will depend on several key components. These factors are the extent of the disease, the patient's history and age, and the location of the tumor.

The most common forms of mesothelioma treatment, for those with pleural mesothelioma, are a pneumonectomy, radiation, chemotherapy, and palliative therapies. One form of mesothelioma treatment is a pneumonectomy, or the removal of the cancerous lung. Depending on the spread of the disease, parts of diaphragm may be removed as well. A pleurectomy may also be used to treat pleural mesothelioma by removing parts of the chest and surrounding tissue. The ability for these procedures to be performed are dependent on the patient's overall health, spread of the disease, and the amount of asbestos exposure.

Radiation treatment is another form of mesothelioma treatment for those suffering from pleural mesothelioma. Radiation therapy works by placing a radioactive source in the area of disease. The use of radiation has the benefit of destroying cancerous tissue while not exposing healthy cells. This form of mesothelioma treatment can be performed in conjunction with surgery or alone if the individual is to ill for surgery.

Chemotherapy is another common form of mesothelioma treatment for those with pleural mesothelioma. This high toxicity drug is usually administered by injection or in pill form. Some side affects from chemotherapy include nausea, vomiting, hair loss, fatigue and weight loss. This form of mesothelioma treatment is not targeted to a particular area like radiation therapy. Therefore, the drugs used have to make their way through the body to the cancerous area or areas. Unfortunately, this has the disadvantage of exposing healthy tissue to the toxicity of the chemotherapy drugs.

Palliative therapies are also used as a form of mesothelioma treatment for those with pleural mesothelioma. This involves removing excess fluid by needle and suction from the affected areas. Drugs are also used in order to keep fluid accumulation under control.

As additional research is performed on pleural mesothelioma more treatment options may become available. Keeping informed of new mesothelioma treatments is paramount if diagnosed with this devastating disease.

Reference: Nick Johnson

1 comment:

  1. I had no idea that they could remove a whole lung! It sounds very dangerous, but I guess if it's worth the risk to get rid of the cancer then it might as well be done. Are drugs like Cisplatin used for treatments as well? I'm not sure if that is a separate drug or if it goes along with chemotherapy. Are those kinds of drugs effective at all?

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