Doctors often rely on knowing the different stages of mesothelioma to be able to effectively treat this type of cancer. Like most other cancers, this type of cancer passes through different stages as the disease advances, these different stages have significant bearing on the type of treatment that will be prescribed and on the most likely outcome of the disease.
The various mesothelioma stages generally indicate how far the disease has progressed beyond its original point of origin. Localized mesothelioma is diagnosed when the cancer has not spread beyond the membrane (most often the lining of the lungs) in which it originated. If the cancer cells have spread beyond this lining to invade the lungs, chest wall cavity or other body organs it is considered an advanced mesothelioma stage, which is much more difficult to treat.
Beyond this informal localized vs. advanced classification, four distinct stages are recognized by each of the two most widely used mesothelioma staging systems. One system, the TNM staging system, is used most often in progressive cancer treatment centers and is recognized by the American Cancer Society as the most accurate mesothelioma staging system. The other, the Butchart Staging System, is the most common system for staging cancer in general.
Butchart Mesothelioma Stages
The Butchart system classifies mesothelioma cancer into four different stages depending on the stage of the main tumor mass.
* Stage I - Cancer is only seen in one side of the chest lining, or pleura
* Stage II - The mesothelioma has spread to any one of the chest wall, esophagus or heart or the lymph nodes of the chest
* Stage III - The cancer has invaded the diaphragm and the lining of the abdominal cavity (peritoneal cancer) or has spread to additional lymph nodes in the body
* Stage IV - Mesothelioma has spread to several major organs The Butchart staging system has been replaced largely by the TNM system for classifying mesothelioma cancer stages.
TNM Staging System
TNM stands for Tumor, Nodes and Metastasis; three keys to determining how advanced mesothelioma cancer is using this system. T stands for the extent of the tumor, N for how advanced the disease is in the lymph nodes and M for the extent of spread of the cancer into other organs.
* Stage I - Mesothelioma is restricted to the pleura of the chest and has not spread to other areas.
* Stage II - The cancer has spread to the pleural lining and to the outer lining of the lung or into the lung itself.
* Stage III - In addition to the pleura, mesothelioma spreads to part of the chest cavity behind the breast bone or within the chest wall. This stage also usually includes cancer of the lymph nodes.
* Stage IV - The most advanced of the mesothelioma stages, when cancer has spread to major organs or the bones or brain. Metastasis refers to the generalized spreading of the cancer.
Each individual case of mesothelioma is different and these stages are not the only factors that determine the type of treatment and the prognosis of the disease. Other factors come into consideration.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Friday, September 24, 2010
Monday, September 20, 2010
Important Nutritional Tips For Mesothelioma Patients Undergoing Chemotherapy.
Chemotherapy is one of the main treatments that cancer patients can to treat the disease. It involves the use of anticancer drugs to kill the cancer cells, however normal cells are also destroyed in the process.
This destruction of cancer cells leaves the body in a weak state. In addition, chemotherapy has a number of side effects, such as nausea. If cancer patients do not eat properly, they can become malnourished and pass away not from cancer, but from an infection or other illness in their weakened state. These are some tips to improve the nutrition of patients undergoing chemotherapy:
1-. Chemotherapy can cause anorexia{poor appetite} so choose foods that really pack a nutritional punch, so when you do eat, even if it is just a small amount, you are consuming nutritional foods high in protein and calories. Keep healthy snacks with you at all times. You should also consider adding daily multivitamin to boost your diet, but you must discuss this with your doctor before you add them.
2- Unfortunately, chemotherapy can also cause constipation and diarrhea - sometimes both in the same patient. To avoid these problems, drink plenty of fluids and avoid anything with caffeine. You may also want to cut most of the dairy out of your diet. Foods with good soluble fiber, such as mashed potatoes and bananas, can also be added to your diet to help with constipation and diarrhea.
3- One of the best ways to boost your diet during chemotherapy is to add as much protein to your diet as possible. Proteins, such as those found in meat, nuts and beans, can help you feel better during treatment, and can help fight cancer more effectively. Even if you do not care for meat or are dealing with anorexia, there are many ways to add protein to your diet. Here are some great tips for integrating protein whenever possible:
* When making pasta, add a beaten egg at the last second. As you stir, the heat will cook the egg, adding a great source of protein.
* Eat peanut butter with fruit.
* Add extra beans to soups and other dishes.
* Add powdered milk to recipes like muffins, mashed potatoes, and meatloaf.
* Prepare protein drinks and keep them with you all day, so you can get protein even just a sip at a time.
* Nuts are a great protein-enriched snack to carry with you throughout the day.
You can talk to a dietician about more ways to add protein to your diet.
4-In addition, if you're dealing with anorexia, your should add many calories to your diet to keep up strength. Some of the best ways to do this include:
* Spread butter or margarine on crackers.
* Stir unsweetened whipped cream into mashed potatoes.
* Add honey to cereal or desserts.
* Sprinkle granola into yogurt.
* Choose dried fruits as a healthy snack, and add them to meals or baked goods when possible.
A mesothelioma patient should seek to know as much as possible about the different methods of treating the disease so that they can cooperate maximally with treatment.
Bello Kamorudeen.http://www.mesotheliomacorner.blogspot.com
This destruction of cancer cells leaves the body in a weak state. In addition, chemotherapy has a number of side effects, such as nausea. If cancer patients do not eat properly, they can become malnourished and pass away not from cancer, but from an infection or other illness in their weakened state. These are some tips to improve the nutrition of patients undergoing chemotherapy:
1-. Chemotherapy can cause anorexia{poor appetite} so choose foods that really pack a nutritional punch, so when you do eat, even if it is just a small amount, you are consuming nutritional foods high in protein and calories. Keep healthy snacks with you at all times. You should also consider adding daily multivitamin to boost your diet, but you must discuss this with your doctor before you add them.
2- Unfortunately, chemotherapy can also cause constipation and diarrhea - sometimes both in the same patient. To avoid these problems, drink plenty of fluids and avoid anything with caffeine. You may also want to cut most of the dairy out of your diet. Foods with good soluble fiber, such as mashed potatoes and bananas, can also be added to your diet to help with constipation and diarrhea.
3- One of the best ways to boost your diet during chemotherapy is to add as much protein to your diet as possible. Proteins, such as those found in meat, nuts and beans, can help you feel better during treatment, and can help fight cancer more effectively. Even if you do not care for meat or are dealing with anorexia, there are many ways to add protein to your diet. Here are some great tips for integrating protein whenever possible:
* When making pasta, add a beaten egg at the last second. As you stir, the heat will cook the egg, adding a great source of protein.
* Eat peanut butter with fruit.
* Add extra beans to soups and other dishes.
* Add powdered milk to recipes like muffins, mashed potatoes, and meatloaf.
* Prepare protein drinks and keep them with you all day, so you can get protein even just a sip at a time.
* Nuts are a great protein-enriched snack to carry with you throughout the day.
You can talk to a dietician about more ways to add protein to your diet.
4-In addition, if you're dealing with anorexia, your should add many calories to your diet to keep up strength. Some of the best ways to do this include:
* Spread butter or margarine on crackers.
* Stir unsweetened whipped cream into mashed potatoes.
* Add honey to cereal or desserts.
* Sprinkle granola into yogurt.
* Choose dried fruits as a healthy snack, and add them to meals or baked goods when possible.
A mesothelioma patient should seek to know as much as possible about the different methods of treating the disease so that they can cooperate maximally with treatment.
Bello Kamorudeen.http://www.mesotheliomacorner.blogspot.com
Saturday, September 18, 2010
Mesothelioma Prognosis - Why Do Some Patients Survive Longer?
There have been some few patients who have survived far beyond the usual one year prognosis for most mesothelioma victims and a handful that have even been cured, with no trace of the aggressive cancer several years after treatment (though recurrence is always possible).
Many medical experts are baffled by this observation and for most of the time they are yet to find a real scientific basis to explain why some mesothelioma patients survive and others do not.
There seems to be one common factor amongst those that have survived the disease for longer times - the immune system. Studies of those who have either survived or been cured of the disease reveal that most of these patients participated in some sort of therapy that enhanced their immune system. Some treatments included clinical trials in immunology while others involved alternative therapies dealing with the immune system.
A number of mesothelioma survivors have posted their stories on the Internet and have spoken to patients and their families with the hope of providing a brighter outlook for their future. These same survivors have also presented their cases to doctors and researchers. The most outspoken of these individuals is Paul Kraus, an Australian mesothelioma survivor. Kraus was diagnosed with abdominal/ peritoneal mesothelioma in 1997, a form of the disease that is tougher to treat than the more common pleural mesothelioma. Kraus worked in a factory 35 years earlier where he was exposed him to blue (crocidolite) asbestos.
Upon his diagnosis, Kraus changed his diet (he's now a vegetarian), added many vitamins and supplements to his daily routine, began "juicing," and tried a treatment known as ozone therapy. Kraus explains, "They took blood out of a vein, used an ozone machine to add ozone (a molecule composed of three oxygen atoms) to the blood and reintroduced it into my body through a drip. The rationale for that was that cancer does not like an oxygenated environment." The research in putting the protocol together took a lot of time, but in the long-run, Kraus believes the combination of all these treatments stabilized his mesothelioma. Today, tests show he still has the disease and his body is a bit weaker than it was, but he has no pain and his doctors tell him he has many more years to live. Kraus stresses the fact that he is not the only mesothelioma survivor.
He has cited the case of a man diagnosed 14 years ago at age 58 (no name given) who had a chest wall resection after diagnosis and has had no symptoms or recurrence since. His doctors believe there was "moderate host inflammatory response" and that spontaneous regression may be an immune-mediated phenomenon" - in other words, his immune system played a role in his survival.
Another survivor, Rhio O'Connor - who recently published a book about his fight with mesothelioma - has lived with the disease for seven years. He opted against the conventional methods of treatment like surgery, chemotherapy and radiotherapy. Instead, with the help of several medical physicians, he developed a regimen that included 100 supplements per day, changed his diet drastically, and now practices what he calls "mind-body medicine" (such as non-stress techniques like meditation). In his book, he recommends a variety of alternatives to traditional medicines and treatments.
All mesothelioma patients should be encouraged to participate in clinical trials especially those that are trying out new methods of boosting the immune system.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Many medical experts are baffled by this observation and for most of the time they are yet to find a real scientific basis to explain why some mesothelioma patients survive and others do not.
There seems to be one common factor amongst those that have survived the disease for longer times - the immune system. Studies of those who have either survived or been cured of the disease reveal that most of these patients participated in some sort of therapy that enhanced their immune system. Some treatments included clinical trials in immunology while others involved alternative therapies dealing with the immune system.
A number of mesothelioma survivors have posted their stories on the Internet and have spoken to patients and their families with the hope of providing a brighter outlook for their future. These same survivors have also presented their cases to doctors and researchers. The most outspoken of these individuals is Paul Kraus, an Australian mesothelioma survivor. Kraus was diagnosed with abdominal/ peritoneal mesothelioma in 1997, a form of the disease that is tougher to treat than the more common pleural mesothelioma. Kraus worked in a factory 35 years earlier where he was exposed him to blue (crocidolite) asbestos.
Upon his diagnosis, Kraus changed his diet (he's now a vegetarian), added many vitamins and supplements to his daily routine, began "juicing," and tried a treatment known as ozone therapy. Kraus explains, "They took blood out of a vein, used an ozone machine to add ozone (a molecule composed of three oxygen atoms) to the blood and reintroduced it into my body through a drip. The rationale for that was that cancer does not like an oxygenated environment." The research in putting the protocol together took a lot of time, but in the long-run, Kraus believes the combination of all these treatments stabilized his mesothelioma. Today, tests show he still has the disease and his body is a bit weaker than it was, but he has no pain and his doctors tell him he has many more years to live. Kraus stresses the fact that he is not the only mesothelioma survivor.
He has cited the case of a man diagnosed 14 years ago at age 58 (no name given) who had a chest wall resection after diagnosis and has had no symptoms or recurrence since. His doctors believe there was "moderate host inflammatory response" and that spontaneous regression may be an immune-mediated phenomenon" - in other words, his immune system played a role in his survival.
Another survivor, Rhio O'Connor - who recently published a book about his fight with mesothelioma - has lived with the disease for seven years. He opted against the conventional methods of treatment like surgery, chemotherapy and radiotherapy. Instead, with the help of several medical physicians, he developed a regimen that included 100 supplements per day, changed his diet drastically, and now practices what he calls "mind-body medicine" (such as non-stress techniques like meditation). In his book, he recommends a variety of alternatives to traditional medicines and treatments.
All mesothelioma patients should be encouraged to participate in clinical trials especially those that are trying out new methods of boosting the immune system.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Thursday, September 16, 2010
Mesothelioma Surgery- What Are Your Options?
There are three main types of surgeries used in the treatment of mesothelioma.
A-Diagnostic surgery: This is used to confirm the diagnosis and locate the tumor. It is usually non invasive {it does not require cutting up the patient surgically}
B-Curative surgery: This involves the removal of as much tumor as possible with the hope of curing the patient. Radiotherapy and or chemotherapy is often used in combination with this type of surgery.
C-Palliative surgery: This form of surgery offers only symptomatic relief. It involves removal of cancer tissue but it does not offer a cure.
These are the different types of surgical procedures available for treatment:
1-Biopsy
This is a diagnostic form of surgery in which the suspected cancer tissue is partially removed and sent to the laboratory for investigations under the microscope to determine whether the cells are cancerous. There are three types of biopsy procedures: a} Cone biopsy is not generally relevant in the diagnosis of mesothelioma. b} Excisional biopsy involves the removal of as much as possible all the cancerous cells for testing. c} Needle aspiration biopsy typically uses a very long needle to remove a sample of cells from the area where the cancer is suspected.
2-Thoracentesis
This surgical procedure is used in the diagnosis of pleural mesothelioma and it is also used as palliative treatment for draining excessive fluids in the pleura in cases of pleural mesothelioma. During thorancentesis, a very long hollow needle is inserted into the pleural space of the lungs and fluid is drained through the needle. The surgery is done under local anesthesia.
Usually before the procedure is carried out, the doctor orders for plain Chest X-ray to see the best location from which to extract the fluid. The drained fluid is then transported to the laboratory for testing.
3-Pleurodesis
This is a palliative surgery usually done for patients with pleural mesothelioma. The pleural spaces are first drained of the excessive fluid accumulation and then a talc-like chemical is inserted into the pleural space that causes inflammation in the pleural space. This obliterates the space and prevents further fluid accumulation.
4-Pneumonectomy
Pneumonectomy is the removal of one of the lungs. This form of surgery is usually used to treat mesothelioma affecting just one lung. It cannot be used for plural mesothelioma affecting both lungs and it is also not suitable for treating advanced cancer that has spread to other parts of the body.
Suitable candidates suitable for this surgery must have a very good general state of health. This operation is done under general anesthesia and the affected lung is removed completely. The patient will have to breathe with assistance of a respirator several days after the surgery.
5-Parencentesis Parencentesis is a form of palliative surgery for peritoneal mesothelioma in which the excessive fluid in the peritoneum (which causes abdominal pain and swelling} is drained through a long, hollow needle inserted into the abdomen.
6-Thoracotomy Thoracotomy is a generic name referring to lung surgery that be performed in patients with pleural mesaothelioma. There are three main types of thoracotomy procedures: A}Wedge resection-it is used to remove small localized tumors leaving as much healthy tissue as possible intact.
B} Lobectomy-this the removal of one or more lobes of the lungs C} Pneumonectomy-this is the removal of the entire lung on one side
7-Thorascocopy This is a procedure that can be used to diagnose pleural mesothelioma and other lung diseases. An incision is made into the chest, and a long tube is inserted into the pleural spaces of the lungs, enabling the doctor/surgeon to examine the pleura. Samples of suspected cancer cells are then removed for testing.
Bello kamorudeen. http://www.mesotheliomacorner.blogspot.com
A-Diagnostic surgery: This is used to confirm the diagnosis and locate the tumor. It is usually non invasive {it does not require cutting up the patient surgically}
B-Curative surgery: This involves the removal of as much tumor as possible with the hope of curing the patient. Radiotherapy and or chemotherapy is often used in combination with this type of surgery.
C-Palliative surgery: This form of surgery offers only symptomatic relief. It involves removal of cancer tissue but it does not offer a cure.
These are the different types of surgical procedures available for treatment:
1-Biopsy
This is a diagnostic form of surgery in which the suspected cancer tissue is partially removed and sent to the laboratory for investigations under the microscope to determine whether the cells are cancerous. There are three types of biopsy procedures: a} Cone biopsy is not generally relevant in the diagnosis of mesothelioma. b} Excisional biopsy involves the removal of as much as possible all the cancerous cells for testing. c} Needle aspiration biopsy typically uses a very long needle to remove a sample of cells from the area where the cancer is suspected.
2-Thoracentesis
This surgical procedure is used in the diagnosis of pleural mesothelioma and it is also used as palliative treatment for draining excessive fluids in the pleura in cases of pleural mesothelioma. During thorancentesis, a very long hollow needle is inserted into the pleural space of the lungs and fluid is drained through the needle. The surgery is done under local anesthesia.
Usually before the procedure is carried out, the doctor orders for plain Chest X-ray to see the best location from which to extract the fluid. The drained fluid is then transported to the laboratory for testing.
3-Pleurodesis
This is a palliative surgery usually done for patients with pleural mesothelioma. The pleural spaces are first drained of the excessive fluid accumulation and then a talc-like chemical is inserted into the pleural space that causes inflammation in the pleural space. This obliterates the space and prevents further fluid accumulation.
4-Pneumonectomy
Pneumonectomy is the removal of one of the lungs. This form of surgery is usually used to treat mesothelioma affecting just one lung. It cannot be used for plural mesothelioma affecting both lungs and it is also not suitable for treating advanced cancer that has spread to other parts of the body.
Suitable candidates suitable for this surgery must have a very good general state of health. This operation is done under general anesthesia and the affected lung is removed completely. The patient will have to breathe with assistance of a respirator several days after the surgery.
5-Parencentesis Parencentesis is a form of palliative surgery for peritoneal mesothelioma in which the excessive fluid in the peritoneum (which causes abdominal pain and swelling} is drained through a long, hollow needle inserted into the abdomen.
6-Thoracotomy Thoracotomy is a generic name referring to lung surgery that be performed in patients with pleural mesaothelioma. There are three main types of thoracotomy procedures: A}Wedge resection-it is used to remove small localized tumors leaving as much healthy tissue as possible intact.
B} Lobectomy-this the removal of one or more lobes of the lungs C} Pneumonectomy-this is the removal of the entire lung on one side
7-Thorascocopy This is a procedure that can be used to diagnose pleural mesothelioma and other lung diseases. An incision is made into the chest, and a long tube is inserted into the pleural spaces of the lungs, enabling the doctor/surgeon to examine the pleura. Samples of suspected cancer cells are then removed for testing.
Bello kamorudeen. http://www.mesotheliomacorner.blogspot.com
Sunday, September 12, 2010
Mesothelioma Treatments-What Are Your Options?
There are several options available for the treatment of mesothelioma. The most recommended forms of treatment are: a} Surgery b} Chemotherapy c} Radiotherapy. There are however other less popular, less commonly used forms of treatments, these include gene therapy, immunotherapy, photodynamic therapy and others. Some of these other forms of treatment are still in the stage of experimental and clinical trials usage.
The cancer is usually treated by the use of combination therapies involving the use of more than one type of therapy. Most times, surgery is used to remove as much of the tumor as possible and this is followed with chemotherapy and or radiotherapy to kill the remaining cancer cells. This particular combination of surgery and chemotherapy with radiotherapy is one of the commonest forms of therapy adopted for treatment.
Alternative therapies are also sometimes used in combination with the traditional treatment options. Many victims seek to add alternative therapies like TENS therapy, acupuncture, or massage to their treatment.
When you or your loved one is diagnosed with mesothelioma, you will have work with your doctor to choose the best treatment plan for you. To make the right choice, you have to know all the options available to you. Having a good knowledge of your chosen treatment option often helps you{the victim} and your family cope and cooperate better with the treatment.
Mesothelioma cure
Mesothelioma is a type of cancer that is notoriously resistant to most forms of treatment. Most of the presently available forms of treatment such as surgery, chemotherapy, and radiotherapy only offer palliative relief and not a cure.
Many scientific studies and clinical trials have tried find a cure for mesothelioma, but all have failed to come up with a cure.
Because mesothelioma is a rare cancer, attracting the necessary funding for the research to find a cure has been difficult, but recently as result increased public awareness about the disease, more people and specific interest groups are beginning to show more interest in supporting research for mesothelioma cure. Once good funding is available for research, the hope for a cure will become a tangible reality in the not too distant future.
Treatment Options
1-Surgery
There are three main types of surgical treatments for mesothelioma: a}diagnostic surgery b}curative surgery c}palliative surgery. Some types of surgeries fall into more than one category. Thorancentesis{removal of fluid from the pleural space}which may be a diagnostic procedure may also be used as a form of palliative treatment to provide symptomatic relief. Curative surgery is aimed at removing if possible all cancerous cells from the body. Curative surgery is only recommended for the early stages of the cancer, that is stage 1 and stage 2.Unfortunately however mesothelioma is not usually diagnosed until it has reached an advanced stage that is stage 3 and stage 4, when curative surgery is no longer relevant.
2-Chemotherapy
Chemotherapy is an effective treatment option but it has a lot of side effects. Chemotherapy involves the use of anticancer drugs which are usually given intravenously. Examples of such drugs are Alimta and Cisplatin. Anti cancer drugs target and kill cancer cells by inhibiting their rapid and haphazard multiplication and division. These drugs are however not specific in their mode of action and they end up killing some normally dividing healthy cells causing most of their unpleasant side effects associated with use of anti cancer drugs.
Newer chemotherapy drugs are generally more effective than the older drugs. A new form of chemotherapy called heated chemotherapy which involves the perfusion of heated chemotherapy drugs into the peritoneum following surgery is used for the treatment of peritoneal mesothelioma.
3-Radiotherapy
Radiotherapy or radiation therapy is the use of high energy rays to kill the cancer cells. This form of therapy is usually used in combination with surgery. Radiotherapy may also be used as a sole therapy to relieve pain and some other symptoms associated with mesothelioma. Radiotherapy generally gives short term symptomatic relief. There are two types of radiotherapy therapies.
a-External beam radiation which is the commoner type in which radiation beam is directed unto the affected area of the body from an external source.
b-Brachytherapy or internal radiotherapy; This is a newer type of radiotherapy in which tiny radioactive rods are implanted into the tumor area of the body to provide a strong concentrated dose of radiation to the tumor while doing very little damage to the surrounding normal healthy tissues.
4-Photodynamic Therapy
This is a form of highly specialized and specific form of treatment that uses light energy to kill cancer cells, it is used to treat skin cancers, some types of lung cancers, and pleural mesothelioma.
This form of treatment is however not suitable for patients with metastasized cancers, it is most effective in patients with localized form of mesothelioma. Photodynamic therapy involves giving the patient an intravenous solution of a medication that makes the cancer cells highly sensitive to a particular kind of light. One to two days after their treatment, the patient is exposed to light, and the cancer cells that have absorbed the medications are killed.
Bello kamorudeen. http://www.mesotheliomacorner.blogspot.com
The cancer is usually treated by the use of combination therapies involving the use of more than one type of therapy. Most times, surgery is used to remove as much of the tumor as possible and this is followed with chemotherapy and or radiotherapy to kill the remaining cancer cells. This particular combination of surgery and chemotherapy with radiotherapy is one of the commonest forms of therapy adopted for treatment.
Alternative therapies are also sometimes used in combination with the traditional treatment options. Many victims seek to add alternative therapies like TENS therapy, acupuncture, or massage to their treatment.
When you or your loved one is diagnosed with mesothelioma, you will have work with your doctor to choose the best treatment plan for you. To make the right choice, you have to know all the options available to you. Having a good knowledge of your chosen treatment option often helps you{the victim} and your family cope and cooperate better with the treatment.
Mesothelioma cure
Mesothelioma is a type of cancer that is notoriously resistant to most forms of treatment. Most of the presently available forms of treatment such as surgery, chemotherapy, and radiotherapy only offer palliative relief and not a cure.
Many scientific studies and clinical trials have tried find a cure for mesothelioma, but all have failed to come up with a cure.
Because mesothelioma is a rare cancer, attracting the necessary funding for the research to find a cure has been difficult, but recently as result increased public awareness about the disease, more people and specific interest groups are beginning to show more interest in supporting research for mesothelioma cure. Once good funding is available for research, the hope for a cure will become a tangible reality in the not too distant future.
Treatment Options
1-Surgery
There are three main types of surgical treatments for mesothelioma: a}diagnostic surgery b}curative surgery c}palliative surgery. Some types of surgeries fall into more than one category. Thorancentesis{removal of fluid from the pleural space}which may be a diagnostic procedure may also be used as a form of palliative treatment to provide symptomatic relief. Curative surgery is aimed at removing if possible all cancerous cells from the body. Curative surgery is only recommended for the early stages of the cancer, that is stage 1 and stage 2.Unfortunately however mesothelioma is not usually diagnosed until it has reached an advanced stage that is stage 3 and stage 4, when curative surgery is no longer relevant.
2-Chemotherapy
Chemotherapy is an effective treatment option but it has a lot of side effects. Chemotherapy involves the use of anticancer drugs which are usually given intravenously. Examples of such drugs are Alimta and Cisplatin. Anti cancer drugs target and kill cancer cells by inhibiting their rapid and haphazard multiplication and division. These drugs are however not specific in their mode of action and they end up killing some normally dividing healthy cells causing most of their unpleasant side effects associated with use of anti cancer drugs.
Newer chemotherapy drugs are generally more effective than the older drugs. A new form of chemotherapy called heated chemotherapy which involves the perfusion of heated chemotherapy drugs into the peritoneum following surgery is used for the treatment of peritoneal mesothelioma.
3-Radiotherapy
Radiotherapy or radiation therapy is the use of high energy rays to kill the cancer cells. This form of therapy is usually used in combination with surgery. Radiotherapy may also be used as a sole therapy to relieve pain and some other symptoms associated with mesothelioma. Radiotherapy generally gives short term symptomatic relief. There are two types of radiotherapy therapies.
a-External beam radiation which is the commoner type in which radiation beam is directed unto the affected area of the body from an external source.
b-Brachytherapy or internal radiotherapy; This is a newer type of radiotherapy in which tiny radioactive rods are implanted into the tumor area of the body to provide a strong concentrated dose of radiation to the tumor while doing very little damage to the surrounding normal healthy tissues.
4-Photodynamic Therapy
This is a form of highly specialized and specific form of treatment that uses light energy to kill cancer cells, it is used to treat skin cancers, some types of lung cancers, and pleural mesothelioma.
This form of treatment is however not suitable for patients with metastasized cancers, it is most effective in patients with localized form of mesothelioma. Photodynamic therapy involves giving the patient an intravenous solution of a medication that makes the cancer cells highly sensitive to a particular kind of light. One to two days after their treatment, the patient is exposed to light, and the cancer cells that have absorbed the medications are killed.
Bello kamorudeen. http://www.mesotheliomacorner.blogspot.com
Friday, September 10, 2010
Mesothelioma Staging Systems-How Do You Stage Mesothelioma
Most known cancers have various staging systems which have been developed to aid doctors and physicians in the diagnosis and treatment of individual cases of cancer.
Pleural mesothelioma is the only form of mesothelioma that has been successfully staged as it is the commonest type of the disease.There are three different staging systems used to determine the extent of pleural mesothelioma, each one of these three different staging systems measure different aspects of the cancer,including the size of the tumor, the level of spreading{metastases}and the probable involvement of lymph nodes. The stage of mesothelioma at the time of diagnosis determines to a very large extent the type of treatment prescribed by the doctor.
Butchart System
The Butchart System is the oldest staging system for malignant mesothelioma and is the one most commonly used by doctors and specialists to diagnose and treat the tumor. The Butchart System is based on the tumor size (mass) and divides malignant mesothelioma into four stages:
* Stage 1 - Malignant mesothelioma has affected the right or left side of the chest cavity (pleural lining) and may be seen in the diaphragm.
* Stage 2 - Malignant mesothelioma has been found in the pleura on both sides of the body and may have also moved into the heart, stomach, or esophagus on both sides. Lymph nodes may be affected.
* Stage 3 - Malignant mesothelioma has reached the abdominal cavity (peritoneum). Lymph nodes past the chest may be affected.
* Stage 4 - Malignant mesothelioma has reached other organs and has entered the blood stream.
TNM System
The TNM System is a more modern staging system for malignant mesothelioma. The TNM System is based on the extent of the tumor, metastasis, and lymph node involvement. Again, the TNM System divides malignant mesothelioma into four stages: * Stage 1 - Malignant mesothelioma is present in the left or right chest cavity (pleura) and may have metastasized to the lung, the sac around the heart (pericardium) or the diaphragm on the same side. Lymph nodes at stage 1 are not involved.
* Stage 2 - Malignant mesothelioma has reached from one side of the chest cavity to a lymph node near the lung area on the same side as the cancer. The cancer has metastasized to the diaphragm, pericardium (sac around the heart), or the lung on the same side as the primary tumor.
* Stage 3 - Malignant mesothelioma has penetrated the chest lining, heart, esophagus, muscle, ribs and vital organs within the chest cavity on the same side as the cancer. Lymph nodes may or may not be involved during this stage.
* Stage 4 - Malignant mesothelioma has metastasized to the pleural area and the lymph nodes on the opposite side of where the cancerous tumor is located. It may also have reached the chest cavities or lungs on both sides, or may have spread to the abdomen.
Brigham System
The Brigham System is the most modern of the three malignant mesothelioma staging systems. The Brigham System looks at different variables such as the involvement of the lymph nodes and the surgical ability to remove a malignant mesothelioma tumor (resectability). For this reason, it is not used very often to stage mesothelioma, as the cancer is rarely operable. The Brigham System divides malignant mesothelioma into four stages:
* Stage 1 - Malignant mesothelioma tumor is still resectable (able to be removed surgically) and the lymph nodes are not affected.
* Stage 2 - Malignant mesothelioma tumor is still resectable, but the lymph nodes are now affected.
* Stage 3 - Malignant mesothelioma tumor is not resectable and the malignant mesothelioma has penetrated the heart, chest wall, abdominal cavity or diaphragm. Lymph nodes may or may not be affected.
* Stage 4 - Malignant mesothelioma tumor is not resectable and has completely metastasized (spread throughout the body).
Process of Staging Malignant Mesothelioma
When mesothelioma is diagnosed by a physician or specialist, they must determine the extent of the cancer and how far it has spread. Most often, they will use imaging procedures to see inside the chest or abdomen to help determine the staging of the malignant mesothelioma. The imaging options physicians may use include: * Chest X-ray * CT scan of the chest and/or abdomen * MRI scan of the chest and/or abdomen * PET of the chest and/or abdomen
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
Pleural mesothelioma is the only form of mesothelioma that has been successfully staged as it is the commonest type of the disease.There are three different staging systems used to determine the extent of pleural mesothelioma, each one of these three different staging systems measure different aspects of the cancer,including the size of the tumor, the level of spreading{metastases}and the probable involvement of lymph nodes. The stage of mesothelioma at the time of diagnosis determines to a very large extent the type of treatment prescribed by the doctor.
Butchart System
The Butchart System is the oldest staging system for malignant mesothelioma and is the one most commonly used by doctors and specialists to diagnose and treat the tumor. The Butchart System is based on the tumor size (mass) and divides malignant mesothelioma into four stages:
* Stage 1 - Malignant mesothelioma has affected the right or left side of the chest cavity (pleural lining) and may be seen in the diaphragm.
* Stage 2 - Malignant mesothelioma has been found in the pleura on both sides of the body and may have also moved into the heart, stomach, or esophagus on both sides. Lymph nodes may be affected.
* Stage 3 - Malignant mesothelioma has reached the abdominal cavity (peritoneum). Lymph nodes past the chest may be affected.
* Stage 4 - Malignant mesothelioma has reached other organs and has entered the blood stream.
TNM System
The TNM System is a more modern staging system for malignant mesothelioma. The TNM System is based on the extent of the tumor, metastasis, and lymph node involvement. Again, the TNM System divides malignant mesothelioma into four stages: * Stage 1 - Malignant mesothelioma is present in the left or right chest cavity (pleura) and may have metastasized to the lung, the sac around the heart (pericardium) or the diaphragm on the same side. Lymph nodes at stage 1 are not involved.
* Stage 2 - Malignant mesothelioma has reached from one side of the chest cavity to a lymph node near the lung area on the same side as the cancer. The cancer has metastasized to the diaphragm, pericardium (sac around the heart), or the lung on the same side as the primary tumor.
* Stage 3 - Malignant mesothelioma has penetrated the chest lining, heart, esophagus, muscle, ribs and vital organs within the chest cavity on the same side as the cancer. Lymph nodes may or may not be involved during this stage.
* Stage 4 - Malignant mesothelioma has metastasized to the pleural area and the lymph nodes on the opposite side of where the cancerous tumor is located. It may also have reached the chest cavities or lungs on both sides, or may have spread to the abdomen.
Brigham System
The Brigham System is the most modern of the three malignant mesothelioma staging systems. The Brigham System looks at different variables such as the involvement of the lymph nodes and the surgical ability to remove a malignant mesothelioma tumor (resectability). For this reason, it is not used very often to stage mesothelioma, as the cancer is rarely operable. The Brigham System divides malignant mesothelioma into four stages:
* Stage 1 - Malignant mesothelioma tumor is still resectable (able to be removed surgically) and the lymph nodes are not affected.
* Stage 2 - Malignant mesothelioma tumor is still resectable, but the lymph nodes are now affected.
* Stage 3 - Malignant mesothelioma tumor is not resectable and the malignant mesothelioma has penetrated the heart, chest wall, abdominal cavity or diaphragm. Lymph nodes may or may not be affected.
* Stage 4 - Malignant mesothelioma tumor is not resectable and has completely metastasized (spread throughout the body).
Process of Staging Malignant Mesothelioma
When mesothelioma is diagnosed by a physician or specialist, they must determine the extent of the cancer and how far it has spread. Most often, they will use imaging procedures to see inside the chest or abdomen to help determine the staging of the malignant mesothelioma. The imaging options physicians may use include: * Chest X-ray * CT scan of the chest and/or abdomen * MRI scan of the chest and/or abdomen * PET of the chest and/or abdomen
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
Wednesday, September 8, 2010
Mesothelioma Diagnosis-How Do You Diagnose Mesothelioma?
Mesothelioma is a serious cancer that advances quickly and aggressively. However the diagnosis of this type of cancer is not usually made until it has reached an advanced stage. This is mainly due to two reasons:
1-Mesothelioma has a very long latency period. In a typical case, between 20 to 50 years elapse between asbestos exposure and the onset of the first symptoms of the disease show up.
2-Most of the early and warning symptoms are not specific to mesothelioma; they often resemble symptoms of other conditions that are much less serious. For example, the early symptoms of pleural mesothelioma may look like those for influenza or pneumonia, and this can result in misdiagnosis.
The First Stages of Diagnosis
Mesothelioma patients are typically diagnosed within three to six months of their first visit to a doctor when they complain of breathing difficulties or chest and abdominal pain.
The first step involved in diagnosis is providing a full and accurate medical history to your doctor, this should include details about current and past health concerns, as well as the types of symptoms you are currently experiencing. A mention of any exposure to asbestos is essential. Without revealing this fact, your doctor may not consider asbestos-related diseases in his or her diagnosis. Next, patients will undergo a physical examination, where a doctor will examine for certain physical signs in different areas of the body that are suggestive of the diagnosis. Most likely, the doctor's next step will be to recommend further testing.
Diagnostic Tests
If your doctor has good clinical suspicion of an asbestos-related disease, he /she will then requests for certain to confirm the presence of mesothelioma, determine the location, size and type of cancer involved, and to determine whether the cancer has spread to other parts of the body. This will often involve imaging tests such as:
-Chest X-ray: This is the most commonly used imaging test for the diagnosis of mesothelioma. Almost all diagnoses will involve an x-ray but a more sophisticated test may follow.
-CT Scan: An x-ray-like procedure in which several x-ray pictures are taken and combined with a computer to produce a detailed image of body tissues. If you undergo a CT scan, you may be given an intravenous injection of dye that helps produce more detailed images.
-PET Scan: Glucose solution is administered via intravenous injection, and a scanner is used to spot deposits of cancer cells. Malignant cells take up and use sugars more quickly than normal cells, so they can be easily distinguished using this procedure.
-MRI Scan: A combination of radio waves and a strong magnetic field is used to create detailed three-dimensional images that can be carefully examined by a radiologist.
Fluid and Tissue Tests
These tests, also known as biopsy tests, involve collecting small samples of fluid or tissue and checking them for the presence of cancer cells. These tests are used to actually make a definitive diagnosis of the cancer. Such tests include:
* Fine Needle Aspiration: Mesothelioma cancers cause fluid to build up in affected locations, such as in the pleural membrane of the lungs. During a fine needle aspiration, the surgeon will remove a fluid sample using a very long, thin and hollow needle.
* Thoracoscopy: Thoracoscopy is used in cases where pleural or pericardial mesothelioma is suspected. During this procedure a very small incision is made in the chest wall, through which a sample of tissue is removed.
* Bronchoscopy and Laparoscopy: These procedures are similar to the thoracoscopy, but are performed on different parts of the body. The bronchoscopy is used to view the trachea and airway, while the laparoscopy is used to remove samples of peritoneal tissue.
* Mediastinoscopy: This procedure is used to view lymph nodes in the chest and neck, to determine if cancer has spread from its point of origin. What Should You Do After Receiving The Diagnosis? If you are diagnosed with mesothelioma, your doctor will recommend an "oncologist" (a doctor who has specialized in the treatment of cancers), who is well-versed in treating the disease and will help determine the best options for treatment.
Patients should also educate themselves about mesothelioma and treatment options and reach out to available resources to make coping with a mesothelioma diagnosis easier.
Bello kamorudeen. http://www.mesotheliomacorner.blogspot.com
1-Mesothelioma has a very long latency period. In a typical case, between 20 to 50 years elapse between asbestos exposure and the onset of the first symptoms of the disease show up.
2-Most of the early and warning symptoms are not specific to mesothelioma; they often resemble symptoms of other conditions that are much less serious. For example, the early symptoms of pleural mesothelioma may look like those for influenza or pneumonia, and this can result in misdiagnosis.
The First Stages of Diagnosis
Mesothelioma patients are typically diagnosed within three to six months of their first visit to a doctor when they complain of breathing difficulties or chest and abdominal pain.
The first step involved in diagnosis is providing a full and accurate medical history to your doctor, this should include details about current and past health concerns, as well as the types of symptoms you are currently experiencing. A mention of any exposure to asbestos is essential. Without revealing this fact, your doctor may not consider asbestos-related diseases in his or her diagnosis. Next, patients will undergo a physical examination, where a doctor will examine for certain physical signs in different areas of the body that are suggestive of the diagnosis. Most likely, the doctor's next step will be to recommend further testing.
Diagnostic Tests
If your doctor has good clinical suspicion of an asbestos-related disease, he /she will then requests for certain to confirm the presence of mesothelioma, determine the location, size and type of cancer involved, and to determine whether the cancer has spread to other parts of the body. This will often involve imaging tests such as:
-Chest X-ray: This is the most commonly used imaging test for the diagnosis of mesothelioma. Almost all diagnoses will involve an x-ray but a more sophisticated test may follow.
-CT Scan: An x-ray-like procedure in which several x-ray pictures are taken and combined with a computer to produce a detailed image of body tissues. If you undergo a CT scan, you may be given an intravenous injection of dye that helps produce more detailed images.
-PET Scan: Glucose solution is administered via intravenous injection, and a scanner is used to spot deposits of cancer cells. Malignant cells take up and use sugars more quickly than normal cells, so they can be easily distinguished using this procedure.
-MRI Scan: A combination of radio waves and a strong magnetic field is used to create detailed three-dimensional images that can be carefully examined by a radiologist.
Fluid and Tissue Tests
These tests, also known as biopsy tests, involve collecting small samples of fluid or tissue and checking them for the presence of cancer cells. These tests are used to actually make a definitive diagnosis of the cancer. Such tests include:
* Fine Needle Aspiration: Mesothelioma cancers cause fluid to build up in affected locations, such as in the pleural membrane of the lungs. During a fine needle aspiration, the surgeon will remove a fluid sample using a very long, thin and hollow needle.
* Thoracoscopy: Thoracoscopy is used in cases where pleural or pericardial mesothelioma is suspected. During this procedure a very small incision is made in the chest wall, through which a sample of tissue is removed.
* Bronchoscopy and Laparoscopy: These procedures are similar to the thoracoscopy, but are performed on different parts of the body. The bronchoscopy is used to view the trachea and airway, while the laparoscopy is used to remove samples of peritoneal tissue.
* Mediastinoscopy: This procedure is used to view lymph nodes in the chest and neck, to determine if cancer has spread from its point of origin. What Should You Do After Receiving The Diagnosis? If you are diagnosed with mesothelioma, your doctor will recommend an "oncologist" (a doctor who has specialized in the treatment of cancers), who is well-versed in treating the disease and will help determine the best options for treatment.
Patients should also educate themselves about mesothelioma and treatment options and reach out to available resources to make coping with a mesothelioma diagnosis easier.
Bello kamorudeen. http://www.mesotheliomacorner.blogspot.com
Sunday, August 29, 2010
Mesothelioma Treatment - How Does the Stage of Tumor Affect the Mode of Treatment For Mesothelioma?
The stage (extent) of a mesothelioma is an important factor in determining treatment options. Treatment option used is also based on the patients state of general health and individual preferences. The stage of the tumor most importantly helps to determine whether the tumor is resectable {operable} or not.
Mesotheliomas are very resistant to treatment irrespective of their stage and it is always very important for the patient to know the goal of his or her own treatment before it is commenced, the patient should know whether the aim of the treatment plan is curative or whether it is palliative. The patient must also be informed about the likely side effects and benefits of the treatment. All these will help the patient to make up his/her mind on the preferred mode of treatment.
Early Stage Mesothelioma
Most stage I and some stage II and III mesotheliomas are potentially resectable, but there are exceptions. Resectability is based not only on the size of the tumor, but also on the histological {cellular type} of the cancer with the epitheliod histological type been the most favorable for surgery. Also the location of the tumor and the general state of health of the victim are also considered before surgery is recommended.
Many patients with resectable pleural mesothelioma undergo pleurectomy/decortication or extrapleural pneumonectomy operations to surgically remove their tumors. Patients with peritoneal mesotheliomas in an early stage might also benefit from surgery. Surgery is more likely to result in long-term benefit in stage I cancers, where there is a better chance that most or all of the cancer can be removed. Some patients can have long remissions after extensive surgery by experts. Surgery may still be helpful for later stage cancers, but the benefits are often temporary.
The use of Chemotherapy and radiotherapy as adjuvant therapy to surgery is also very common, they may also be used as the main therapy in early stage of the tumor if the tumor is not operable due to a poor general state of health.
Other forms of surgery for palliative purposes like thorancentesis can also used to alleviate symptoms in the early stages of the cancer.
Finally a patient can also opt to take part in a clinical trial to help to discover new forms of treatment.
Late Stage Mesothelioma
Stage IV mesotheliomas, as well as many earlier stage mesotheliomas, are not resectable by surgery because of the extent of the disease or because a person may not be able to tolerate an operation. The main treatment options at these stage include chemotherapy and radiotherapy to shrink the tumor mass and relieve some of the symptoms of the diseases. The aim of treatment at this stage is not curative and these modes of treatments have serious side effects which the patient must be aware of. Patient should also consider taking part in available clinical trials as there is little hope of survival using the conventional methods of treatment.
Pain management is another important aspect of the care of terminally ill patients. Some minor operations and types of radiation therapy can help relieve pain if needed. Doctors can also prescribe strong pain-relieving drugs. Some people with cancer may hesitate to use opioid drugs (such as morphine) for fear of being sleepy all the time or becoming addicted to them. But many people get very effective pain relief from these medicines without serious side effects. It's very important to let your doctor know if you are having pain so that it can be treated effectively.
Recurrent mesotheliomas
Some mesotheliomas may recur (come back) after the initial treatment. If this happens, further treatment options depend on the location of the cancer and the kind of treatment that was previously prescribed for the patient. Most of the time treatment is limited only to palliative treatments. Chemotherapy could be used to shrink the tumor and provide relief for symptoms. Clinical trials should be highly considered as there is very little hope of any improvement with the use of traditional treatments.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Mesotheliomas are very resistant to treatment irrespective of their stage and it is always very important for the patient to know the goal of his or her own treatment before it is commenced, the patient should know whether the aim of the treatment plan is curative or whether it is palliative. The patient must also be informed about the likely side effects and benefits of the treatment. All these will help the patient to make up his/her mind on the preferred mode of treatment.
Early Stage Mesothelioma
Most stage I and some stage II and III mesotheliomas are potentially resectable, but there are exceptions. Resectability is based not only on the size of the tumor, but also on the histological {cellular type} of the cancer with the epitheliod histological type been the most favorable for surgery. Also the location of the tumor and the general state of health of the victim are also considered before surgery is recommended.
Many patients with resectable pleural mesothelioma undergo pleurectomy/decortication or extrapleural pneumonectomy operations to surgically remove their tumors. Patients with peritoneal mesotheliomas in an early stage might also benefit from surgery. Surgery is more likely to result in long-term benefit in stage I cancers, where there is a better chance that most or all of the cancer can be removed. Some patients can have long remissions after extensive surgery by experts. Surgery may still be helpful for later stage cancers, but the benefits are often temporary.
The use of Chemotherapy and radiotherapy as adjuvant therapy to surgery is also very common, they may also be used as the main therapy in early stage of the tumor if the tumor is not operable due to a poor general state of health.
Other forms of surgery for palliative purposes like thorancentesis can also used to alleviate symptoms in the early stages of the cancer.
Finally a patient can also opt to take part in a clinical trial to help to discover new forms of treatment.
Late Stage Mesothelioma
Stage IV mesotheliomas, as well as many earlier stage mesotheliomas, are not resectable by surgery because of the extent of the disease or because a person may not be able to tolerate an operation. The main treatment options at these stage include chemotherapy and radiotherapy to shrink the tumor mass and relieve some of the symptoms of the diseases. The aim of treatment at this stage is not curative and these modes of treatments have serious side effects which the patient must be aware of. Patient should also consider taking part in available clinical trials as there is little hope of survival using the conventional methods of treatment.
Pain management is another important aspect of the care of terminally ill patients. Some minor operations and types of radiation therapy can help relieve pain if needed. Doctors can also prescribe strong pain-relieving drugs. Some people with cancer may hesitate to use opioid drugs (such as morphine) for fear of being sleepy all the time or becoming addicted to them. But many people get very effective pain relief from these medicines without serious side effects. It's very important to let your doctor know if you are having pain so that it can be treated effectively.
Recurrent mesotheliomas
Some mesotheliomas may recur (come back) after the initial treatment. If this happens, further treatment options depend on the location of the cancer and the kind of treatment that was previously prescribed for the patient. Most of the time treatment is limited only to palliative treatments. Chemotherapy could be used to shrink the tumor and provide relief for symptoms. Clinical trials should be highly considered as there is very little hope of any improvement with the use of traditional treatments.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Tuesday, August 24, 2010
Mesothelioma Prognosis - What Are Your Chances?
About 2000 to 3000 new cases of mesothelioma are diagnosed each year in the United States. Once a patient receives a diagnosis of this cancer, his or her physician will most likely discuss the prognosis or probable course and outcome of the disease with the patient.
Factors That Determine Prognosis
Most times a diagnosis of mesothelioma is made when the cancer has reached an advanced stage as it usually takes a very long amount of time after the contact with asbestos before most victims start displaying the symptoms associated with the disease.
In addition to this fact, even when the symptoms of this cancer do eventually surface, they often resemble the symptoms of more general diseases like pneumonia, influenza and some other lung diseases. This fact coupled with the long delay in appearance of symptoms makes the accurate diagnosis of mesothelioma a very difficult one.
Thus as result of these factors, prognosis for majority of the patients is poor, but many doctors recommend treatment options like surgery, chemotherapy, and radiotherapy to help combat the disease.
Factors that affect prognosis include:
A} The stage of the cancer:
Medically the progression of the cancer is classified in form of stages. The stages range from stage one to stage four. The higher the stage the, the more advanced the cancer. Unfortunately, once the cancer has reached stages three to stage four, treatment options become limited and less effective. In stage four of the cancer, the cancer has spread to other parts of the body and the tumor has often deeply eaten into various key organs and tissues in the body. Stage 4 is not suitable for surgery. Generally the higher the stage of the cancer the worse the prognosis.
B} Histological type of cancer:
Histology refers to the basic cell structure and type of the cancer. Histologically, there are four types of mesothelioma:a}Epithelial,b}Sarcomatoid c}Biphasic{mixed} d}Desmoplastic{variant of sarcomatoid}.Epithelial mesothelioma has a better prognosis than the other types and the sarcomatoid form has the worst prognosis.
C} Age and general condition of victim
Malignant mesothelioma is often diagnosed in people above the age of 55 years old, although there may be exceptions. So some of the victims would have developed chronic diseases associated with old age like diabetes and hypertension and this worsens their prognosis.
D} The size of the tumor
E} The location of the tumor and whether the tumor is operable{whether it can be removed surgically}
F} The extent of other symptoms, including fluid in the lungs or abdomen.
G} Whether or not the patient is a smoker.
When discussing the survival rate of any cancer, references are often made to the "five year survival rate". The five year survival rate refers to the percentage of patients who live at least five years after receiving their diagnosis. According to the American Cancer Society, the five year survival relative survival rate for mesothelioma is approximately 10%.The number has improved over the last five years up from the 9% reported at the end of 2002. In general, the average length of survival reported throughout the last five years has been 10-11 months after diagnosis.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
Factors That Determine Prognosis
Most times a diagnosis of mesothelioma is made when the cancer has reached an advanced stage as it usually takes a very long amount of time after the contact with asbestos before most victims start displaying the symptoms associated with the disease.
In addition to this fact, even when the symptoms of this cancer do eventually surface, they often resemble the symptoms of more general diseases like pneumonia, influenza and some other lung diseases. This fact coupled with the long delay in appearance of symptoms makes the accurate diagnosis of mesothelioma a very difficult one.
Thus as result of these factors, prognosis for majority of the patients is poor, but many doctors recommend treatment options like surgery, chemotherapy, and radiotherapy to help combat the disease.
Factors that affect prognosis include:
A} The stage of the cancer:
Medically the progression of the cancer is classified in form of stages. The stages range from stage one to stage four. The higher the stage the, the more advanced the cancer. Unfortunately, once the cancer has reached stages three to stage four, treatment options become limited and less effective. In stage four of the cancer, the cancer has spread to other parts of the body and the tumor has often deeply eaten into various key organs and tissues in the body. Stage 4 is not suitable for surgery. Generally the higher the stage of the cancer the worse the prognosis.
B} Histological type of cancer:
Histology refers to the basic cell structure and type of the cancer. Histologically, there are four types of mesothelioma:a}Epithelial,b}Sarcomatoid c}Biphasic{mixed} d}Desmoplastic{variant of sarcomatoid}.Epithelial mesothelioma has a better prognosis than the other types and the sarcomatoid form has the worst prognosis.
C} Age and general condition of victim
Malignant mesothelioma is often diagnosed in people above the age of 55 years old, although there may be exceptions. So some of the victims would have developed chronic diseases associated with old age like diabetes and hypertension and this worsens their prognosis.
D} The size of the tumor
E} The location of the tumor and whether the tumor is operable{whether it can be removed surgically}
F} The extent of other symptoms, including fluid in the lungs or abdomen.
G} Whether or not the patient is a smoker.
When discussing the survival rate of any cancer, references are often made to the "five year survival rate". The five year survival rate refers to the percentage of patients who live at least five years after receiving their diagnosis. According to the American Cancer Society, the five year survival relative survival rate for mesothelioma is approximately 10%.The number has improved over the last five years up from the 9% reported at the end of 2002. In general, the average length of survival reported throughout the last five years has been 10-11 months after diagnosis.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
Friday, August 20, 2010
Mesothelioma Alternative Therapy - What Are Your Options?
Quite a number of patients afflicted with asbestos related diseases such as asbestosis and mesothelioma now-a days use different types of complimentary and alternative therapies in addition to conventional therapies like surgery and drugs.
These alternative therapies are used by patients coping with asbestos related disease as a form of pain management, to improve general health, and also to provide symptomatic relief.
Although these treatments do not offer a cure, they certainly help you to live more comfortable lives by providing relief from pain and stress.
The most commonly used alternative therapies include the following:
1} Acupuncture
This is one of the commonest forms of available alternative therapies today, and there are a lot of insurance companies offering coverage for this type of treatment. Acupuncture involves the insertion of extremely fine needles into pressure points at clearly defined locations in the skin to improve the balance and flow of factors called the Yin, Yang, Qi and Blood in traditional Chinese medicine.
This form of treatment provides relief from chronic pain, inflammation, anxiety and stress and it is one of the most commonly used alternative medicines in the treatment of asbestos related diseases.
2} Aromatherapy
This form of alternative therapy involves the use of fragrances to improve physical and psychological well being. The fragrances are applied in liquids called essential oils, which are distilled and highly concentrated plant based oils. Aromatherapists use these fragrances combined in the oils to provide pain relief and to improve the general well being of the patient.
Aromatherapy is often combined with massage , you receive a massage with carrier oils that have been mixed with small amounts of essential oil fragrances.
3} Massage
Massage therapy has been shown to provide a number of important health benefits. It improves blood and lymphatic flow and it is used to improve blood circulation. It also improves muscle tension.
Massage also stimulates nervous and digestive systems, relieve chronic pain and improve skin function. Many patients find this type of therapy useful in reducing anxiety and stress as well as reducing chronic pain.
4} Meditation
Meditation is a well known way of relieving stress, anxiety and depression. Meditation is now also used to manage pain and other symptoms of diseases. Many cancer patients add meditation to their treatment schedules to help to reduce pain, stress and anxiety. Certain studies have shown that meditation may be able to reduce tumor growth and improve your prognosis.
5} Supplements
Dietary supplements include vitamins, minerals, herbs, and amino acids. Vitamins, minerals, and amino acids are all needed by the body to carry out essential life functions, and supplements can help provide necessary chemicals when diet alone cannot. Many herbs can help treat diseases and conditions, as well as provide symptomatic relief. For example, flaxseed, ginseng, and garlic are all known to reduce blood pressure.
When it comes to supplements, it's very important to let your physician know the kind of supplements you are taking, as they can affect how well your prescription medications work. Some supplements can even have dangerous interactive effects when taken in conjunction with certain prescription medications.
6} TENS Therapy
Transcutaneous Electrical Nerve Stimulation - commonly known as TENS therapy - is somewhat similar to acupuncture, in that this treatment stimulates certain defined body locations. However, while acupuncture uses fine needles, TENS therapy stimulates body points with the use of electrodes that deliver very mild electrical shocks.
Unlike many other types of complementary and alternative therapy, TENS has actually been approved by the FDA. While this doesn't automatically mean that TENS can provide a cure when it is used, it does mean that the treatment has been determined to be safe according to FDA regulations, and also means that TENS therapy is covered by insurance.
7} Yoga
The origins of yoga lie in India, where this ancient art is practiced more for spiritual reasons than for health-related reasons. Outside of India, yoga has become a popular form of exercise that is physically and psychologically calming and strengthening. Learning simple yoga techniques can help improve general health by toning and strengthening muscles, improving flexibility, and improving general health and one's state of mind.
8} Pet Therapy
Also known as animal-assisted therapy or animal-assisted activities, this type of therapy aims to improve the general health and well-being of patients by allowing them to interact with a variety of animals. The wonderful effects of animal interaction has long been known - the simple act of stroking a cat or dog can improve the mood, lift the spirits, and even provide some physical benefits (such as the temporary lowering of blood pressure). Pet therapy techniques can be used for a wide variety of medical conditions. For example, a physical therapist working with a person recovering from a stroke might bring a dog to a therapy session and have the patient brush the dog to help improve their motor skills.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
These alternative therapies are used by patients coping with asbestos related disease as a form of pain management, to improve general health, and also to provide symptomatic relief.
Although these treatments do not offer a cure, they certainly help you to live more comfortable lives by providing relief from pain and stress.
The most commonly used alternative therapies include the following:
1} Acupuncture
This is one of the commonest forms of available alternative therapies today, and there are a lot of insurance companies offering coverage for this type of treatment. Acupuncture involves the insertion of extremely fine needles into pressure points at clearly defined locations in the skin to improve the balance and flow of factors called the Yin, Yang, Qi and Blood in traditional Chinese medicine.
This form of treatment provides relief from chronic pain, inflammation, anxiety and stress and it is one of the most commonly used alternative medicines in the treatment of asbestos related diseases.
2} Aromatherapy
This form of alternative therapy involves the use of fragrances to improve physical and psychological well being. The fragrances are applied in liquids called essential oils, which are distilled and highly concentrated plant based oils. Aromatherapists use these fragrances combined in the oils to provide pain relief and to improve the general well being of the patient.
Aromatherapy is often combined with massage , you receive a massage with carrier oils that have been mixed with small amounts of essential oil fragrances.
3} Massage
Massage therapy has been shown to provide a number of important health benefits. It improves blood and lymphatic flow and it is used to improve blood circulation. It also improves muscle tension.
Massage also stimulates nervous and digestive systems, relieve chronic pain and improve skin function. Many patients find this type of therapy useful in reducing anxiety and stress as well as reducing chronic pain.
4} Meditation
Meditation is a well known way of relieving stress, anxiety and depression. Meditation is now also used to manage pain and other symptoms of diseases. Many cancer patients add meditation to their treatment schedules to help to reduce pain, stress and anxiety. Certain studies have shown that meditation may be able to reduce tumor growth and improve your prognosis.
5} Supplements
Dietary supplements include vitamins, minerals, herbs, and amino acids. Vitamins, minerals, and amino acids are all needed by the body to carry out essential life functions, and supplements can help provide necessary chemicals when diet alone cannot. Many herbs can help treat diseases and conditions, as well as provide symptomatic relief. For example, flaxseed, ginseng, and garlic are all known to reduce blood pressure.
When it comes to supplements, it's very important to let your physician know the kind of supplements you are taking, as they can affect how well your prescription medications work. Some supplements can even have dangerous interactive effects when taken in conjunction with certain prescription medications.
6} TENS Therapy
Transcutaneous Electrical Nerve Stimulation - commonly known as TENS therapy - is somewhat similar to acupuncture, in that this treatment stimulates certain defined body locations. However, while acupuncture uses fine needles, TENS therapy stimulates body points with the use of electrodes that deliver very mild electrical shocks.
Unlike many other types of complementary and alternative therapy, TENS has actually been approved by the FDA. While this doesn't automatically mean that TENS can provide a cure when it is used, it does mean that the treatment has been determined to be safe according to FDA regulations, and also means that TENS therapy is covered by insurance.
7} Yoga
The origins of yoga lie in India, where this ancient art is practiced more for spiritual reasons than for health-related reasons. Outside of India, yoga has become a popular form of exercise that is physically and psychologically calming and strengthening. Learning simple yoga techniques can help improve general health by toning and strengthening muscles, improving flexibility, and improving general health and one's state of mind.
8} Pet Therapy
Also known as animal-assisted therapy or animal-assisted activities, this type of therapy aims to improve the general health and well-being of patients by allowing them to interact with a variety of animals. The wonderful effects of animal interaction has long been known - the simple act of stroking a cat or dog can improve the mood, lift the spirits, and even provide some physical benefits (such as the temporary lowering of blood pressure). Pet therapy techniques can be used for a wide variety of medical conditions. For example, a physical therapist working with a person recovering from a stroke might bring a dog to a therapy session and have the patient brush the dog to help improve their motor skills.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Tuesday, August 17, 2010
Mesothelioma Lawyers - Three Crucial Questions You Must Ask Your Lawyer
After receiving a diagnosis of mesothelioma you have to look for a reputable and qualified mesothelioma Lawyer to litigate your case for you. As a mesothelioma victim you are entitled to receiving substantial monetary compensation from the company that probably exposed you to the harmful effects of asbestos fibers which led to your development of the cancer.
Choosing your mesothelioma lawyer can be daunting task, you just have to choose right or else you stand the chance of loosing out on getting the compensation you deserve. Your Lawyer will determine whether or not you are successful in your mesothelioma Lawsuit
Before you make up your mind on your choice of Lawyer you have to set up a meeting with your prospective Lawyers and make sure you ask them the following questions:
1- Ask about the experience of your Lawyers in handling these type of cases, the number of mesothelioma lawsuits they have handled, how much compensation were they able to get for their clients. Ask for documented evidence if necessary to back up their claims.
2- Ask about the costs of the Lawsuit and the amount of fees they are going to charge, are they going to collect their money upfront or do they charge contingency fees. Contingency fees are a percentage of the compensation you receive. If you do not get compensated the Lawyers do not receive any money. This is the common type of financial arrangement that most mesothelioma Lawyers use. You must make sure you agree with your Lawyer on the percentage of the compensation that the lawyer will get before the case commences, most lawyers ask for 30 -40% of the compensation.
3- Ask your Lawyers whether they are the ones that will actually litigate your case or will they be passing the case to another Law firm to actually litigate for them. If this is the case then the Lawyers are not good enough for you and you must look for other ones.
Although the process of choosing the best Lawyer can be a very challenging one, you will be glad you went through all the stress when they get you the compensation you desire.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Choosing your mesothelioma lawyer can be daunting task, you just have to choose right or else you stand the chance of loosing out on getting the compensation you deserve. Your Lawyer will determine whether or not you are successful in your mesothelioma Lawsuit
Before you make up your mind on your choice of Lawyer you have to set up a meeting with your prospective Lawyers and make sure you ask them the following questions:
1- Ask about the experience of your Lawyers in handling these type of cases, the number of mesothelioma lawsuits they have handled, how much compensation were they able to get for their clients. Ask for documented evidence if necessary to back up their claims.
2- Ask about the costs of the Lawsuit and the amount of fees they are going to charge, are they going to collect their money upfront or do they charge contingency fees. Contingency fees are a percentage of the compensation you receive. If you do not get compensated the Lawyers do not receive any money. This is the common type of financial arrangement that most mesothelioma Lawyers use. You must make sure you agree with your Lawyer on the percentage of the compensation that the lawyer will get before the case commences, most lawyers ask for 30 -40% of the compensation.
3- Ask your Lawyers whether they are the ones that will actually litigate your case or will they be passing the case to another Law firm to actually litigate for them. If this is the case then the Lawyers are not good enough for you and you must look for other ones.
Although the process of choosing the best Lawyer can be a very challenging one, you will be glad you went through all the stress when they get you the compensation you desire.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Saturday, August 14, 2010
Abdominal-Peritoneal Mesothelioma Info
Mesothelioma tumors of the peritoneum include benign, malignant and cystic.
Although peritoneal mesothelioma is the most common of these, it is very rare with an annual incidence of 1-2 cases per million persons. Only 10-20 percent of all mesotheliomas arise in the peritoneum. Peritoneal malignant mesothelioma occurs more commonly in adult males but also occurs rarely in children with equal sex incidence.
Malignant mesothelioma occurs mainly late in the fifth decade of life, the benign type in the fourth decade and the cystic type in the third decade. The non malignant type are common in women.
Cause:
The link with asbestos exposure which is well established for pleural mesothelioma is not clear for peritoneal mesothelioma.
Symptoms and Signs
-Abdominal pain which may not be limited to any specific region of the abdomen but may be migratory.
-Abdominal distention and complaints associated with partial bowel obstruction are frequent
-Ascites (fluid in the abdomen,) may be present
-Abdominal mass/swelling may be present
Diagnosis
-CT scans frequently show tumor masses and ascites (fluid in the abdomen)
-Laparatomy and laparoscopy for multiple biopsies {the surgeon opens up the abdomen surgically to look into the peritoneum directly and take samples}
Treatment of Peritoneal Mesothelioma
It is treated with combination therapy:
A. Peritoneal radioactive P32 followed by whole abdomen radiation is used often
B. Chemotherapy:Combination chemotherapy with doxorubicin is a very important secondary component.
C. Surgery:Surgical treatment is done mainly to debulk (reduce the size of the tumor by cutting of parts of the tumor,) and treatment of intestinal obstruction.
Prognosis of Peritoneal Mesothelioma
The prognosis of peritoneal mesothelioma is dismal with median survival of about 1 year after presentation. Death usually results from progressive bowel obstruction.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Although peritoneal mesothelioma is the most common of these, it is very rare with an annual incidence of 1-2 cases per million persons. Only 10-20 percent of all mesotheliomas arise in the peritoneum. Peritoneal malignant mesothelioma occurs more commonly in adult males but also occurs rarely in children with equal sex incidence.
Malignant mesothelioma occurs mainly late in the fifth decade of life, the benign type in the fourth decade and the cystic type in the third decade. The non malignant type are common in women.
Cause:
The link with asbestos exposure which is well established for pleural mesothelioma is not clear for peritoneal mesothelioma.
Symptoms and Signs
-Abdominal pain which may not be limited to any specific region of the abdomen but may be migratory.
-Abdominal distention and complaints associated with partial bowel obstruction are frequent
-Ascites (fluid in the abdomen,) may be present
-Abdominal mass/swelling may be present
Diagnosis
-CT scans frequently show tumor masses and ascites (fluid in the abdomen)
-Laparatomy and laparoscopy for multiple biopsies {the surgeon opens up the abdomen surgically to look into the peritoneum directly and take samples}
Treatment of Peritoneal Mesothelioma
It is treated with combination therapy:
A. Peritoneal radioactive P32 followed by whole abdomen radiation is used often
B. Chemotherapy:Combination chemotherapy with doxorubicin is a very important secondary component.
C. Surgery:Surgical treatment is done mainly to debulk (reduce the size of the tumor by cutting of parts of the tumor,) and treatment of intestinal obstruction.
Prognosis of Peritoneal Mesothelioma
The prognosis of peritoneal mesothelioma is dismal with median survival of about 1 year after presentation. Death usually results from progressive bowel obstruction.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Friday, August 13, 2010
Mesothelioma and Asbestos
Asbestos is a fibrous material which has been in use for a long time mainly for its fire resistant qualities. Asbestos is a preferred building material due to its fire resistant and heat resistant capability coupled with the fact that it is not expensive.
Asbestos was very popular amongst California business owners in the early and mid 20's and they used it in nearly every way they could. They tried to use asbestos to create safer, and cheaper buildings, but time has proven that these building are not any safer, nor are they more cheaper,as the high cost of treating the mesothelioma disease that they caused, they also lead to loss of lives.
Asbestos was once used in everything from automotive parts, clothing, and blankets. It was a natural choice for fire fighter gear. The asbestos material, looked like it was the absolute safest and most rewarding discovery of the 20th century, with buildings, homes, and businesses less likely to burn to the ground with the use of asbestos. The fact that about 3000 people died annually from Mesothelioma , made people to start to see things differently after some time.
Mesothelioma is a direct and profound consequence of long term exposure to asbestos. Asbestos fibers are in fact the only known cause of Mesothelioma. The great tragedy of Mesothelioma is far more insidious than the fact that thousands of people are diagnosed with Mesothelioma every year, but that the knowledge of what asbestos may very well do to the interior of those who were around it regularly has been well known since the 1920s.
Mesothelioma is one of the deadliest diseases with a virtual 100% mortality rate.Most cases will die within a year or two. The material that was often used to protect buildings from fire damage affected the internal organs of the people who worked with it, sentencing these hard working Californians early and painful deaths.
Asbestos affects slowly the lining of the organs, usually attacking the lining of the lungs. It may take somewhere between 10 and 40 years before the damage from asbestos becomes evident in the form of Mesothelioma. Those who worked with it never felt ill or had any physical warning signs that there was anything wrong.
The mortality rate has decreased slightly, as those who are now aware that they worked with asbestos in the past are receiving medical evaluations prior to having symptoms. Unfortunately, many of these individuals are finding their vigilance was warranted. However, with early detection, the survival rate has increased slightly.
For so many, early detection was never a possibility. So few companies were willing to inform their employees that they had been exposed to asbestos for fear of being compelled to reach reasonable and fair financial settlements with the victims of Mesothelioma and their families. Companies which had saved so much by effectively placing their employees at considerable risk need qualified California mesothelioma lawyers to stand up to them in order to provide financial relief from the devastation caused by asbestos.
Mesothelioma lawsuits are unfortunately the only available method of holding companies responsible for their asbestos negligence. A valid mesothelioma lawsuit will not only assists the victim in covering his astronomical medical expenses, but they also help to create awareness and ethical actions by other companies faced with choices during construction.
California mesothelioma lawyers who have excelled in the representation of Mesothelioma victims have surpassed most attorneys in providing aggressive care and representation for their clients. Mesothelioma has become such a glaring example of lack of company concern for their valuable employees. Big companies are required to examine their practices and their human obligation because of Mesothelioma lawsuits and the vast expense of Mesothelioma settlements.
Most of the companies chose to provide less than adequate protection for their workers but chose to provide good fire protection for their buildings. They did not mind some of their workers falling ill of even dying as long as they were able to preserve their buildings.
California workers have had enough of California bad business practice of placing production and performance over the health of their workers. The public needs to let these exploitative Carlifornia companies know that they would not allow them to exploit them any longer, they must challenge them in courts through the use of Mesothelioma lawsuits.
Bello Kamorudeen.http://www.mesotheliomacorner.blogspot.com
Asbestos was very popular amongst California business owners in the early and mid 20's and they used it in nearly every way they could. They tried to use asbestos to create safer, and cheaper buildings, but time has proven that these building are not any safer, nor are they more cheaper,as the high cost of treating the mesothelioma disease that they caused, they also lead to loss of lives.
Asbestos was once used in everything from automotive parts, clothing, and blankets. It was a natural choice for fire fighter gear. The asbestos material, looked like it was the absolute safest and most rewarding discovery of the 20th century, with buildings, homes, and businesses less likely to burn to the ground with the use of asbestos. The fact that about 3000 people died annually from Mesothelioma , made people to start to see things differently after some time.
Mesothelioma is a direct and profound consequence of long term exposure to asbestos. Asbestos fibers are in fact the only known cause of Mesothelioma. The great tragedy of Mesothelioma is far more insidious than the fact that thousands of people are diagnosed with Mesothelioma every year, but that the knowledge of what asbestos may very well do to the interior of those who were around it regularly has been well known since the 1920s.
Mesothelioma is one of the deadliest diseases with a virtual 100% mortality rate.Most cases will die within a year or two. The material that was often used to protect buildings from fire damage affected the internal organs of the people who worked with it, sentencing these hard working Californians early and painful deaths.
Asbestos affects slowly the lining of the organs, usually attacking the lining of the lungs. It may take somewhere between 10 and 40 years before the damage from asbestos becomes evident in the form of Mesothelioma. Those who worked with it never felt ill or had any physical warning signs that there was anything wrong.
The mortality rate has decreased slightly, as those who are now aware that they worked with asbestos in the past are receiving medical evaluations prior to having symptoms. Unfortunately, many of these individuals are finding their vigilance was warranted. However, with early detection, the survival rate has increased slightly.
For so many, early detection was never a possibility. So few companies were willing to inform their employees that they had been exposed to asbestos for fear of being compelled to reach reasonable and fair financial settlements with the victims of Mesothelioma and their families. Companies which had saved so much by effectively placing their employees at considerable risk need qualified California mesothelioma lawyers to stand up to them in order to provide financial relief from the devastation caused by asbestos.
Mesothelioma lawsuits are unfortunately the only available method of holding companies responsible for their asbestos negligence. A valid mesothelioma lawsuit will not only assists the victim in covering his astronomical medical expenses, but they also help to create awareness and ethical actions by other companies faced with choices during construction.
California mesothelioma lawyers who have excelled in the representation of Mesothelioma victims have surpassed most attorneys in providing aggressive care and representation for their clients. Mesothelioma has become such a glaring example of lack of company concern for their valuable employees. Big companies are required to examine their practices and their human obligation because of Mesothelioma lawsuits and the vast expense of Mesothelioma settlements.
Most of the companies chose to provide less than adequate protection for their workers but chose to provide good fire protection for their buildings. They did not mind some of their workers falling ill of even dying as long as they were able to preserve their buildings.
California workers have had enough of California bad business practice of placing production and performance over the health of their workers. The public needs to let these exploitative Carlifornia companies know that they would not allow them to exploit them any longer, they must challenge them in courts through the use of Mesothelioma lawsuits.
Bello Kamorudeen.http://www.mesotheliomacorner.blogspot.com
Tuesday, August 10, 2010
Mesothelioma Blood Test-Mesomark Test
The reason for high death rates among mesothelioma patients is the aggressive nature of the disease and the inability to diagnose it until it is well advanced. Because mesothelioma symptoms do not show up until about 40-50 years after exposure to asbestos, most cases at the time of diagnosis have already reached Stage III or IV. As a result, mesothelioma treatment options are often more palliative than curative.
However, the ability to diagnose the disease at an earlier time would certainly result in a better prognosis for mesothelioma patients. That ability is now present in the form of a mesothelioma blood test known as Mesomark. Developed by Fujirebio Diagnostics Inc. of Malvern, Pennsylvania, a leader in the field of oncology testing, the test measures the amount of a particular biomarker in human serum.
The test was first released in Australia in March 2005 and distribution expanded to Europe just a few months later. Food and Drug Administration approval for the blood test was received nearly two years later in January 2007.
Testing for Mesothelioma
Mesomark is an easily performed blood test that uses an enzyme-linked immunosorbent assay to measure the amount of Soluble Mesothelin-Related Peptides (SMRP) in human serum. SMRP is a biomarker that is produced by mesothelioma cells, and this biomarker may be elevated in the serum of patients who have mesothelioma. The detection of the biomarker through a blood test can help attain an early diagnosis, resulting in more treatment options and a better prognosis for patients.
Mesomark is what is referred to as an in-vitro test. In this test, the blood that is drawn from the patient is sent to a laboratory to measure the level of SMRP. This is performed by using monoclonal antibodies that are known to specifically bind to SMRP. Measuring the amount of bound antibodies in the blood indicates the amount of SMRP, and certain levels indicate the presence of mesothelioma. In addition to detecting the presence of mesothelioma in yet-to-be-diagnosed patients, the Mesomark blood test may also be used to monitor the success of treatments in patients who have already been diagnosed with the disease.
These tests will also help determine the next course of treatment.
The Mesomark blood test has NOT yet been approved for the early diagnosis of mesothelioma.
This test has been approved as a Humanitarian Use Device (HUD), meaning that physicians must follow certain procedures to qualify their patients for testing. Once the physician is certified, informational brochures will be sent to be distributed to each applicable patient.
Those wishing to take part in Mesomark testing will be asked to provide one or more samples of blood. The blood samples will then be sent to a national reference laboratory for testing. In conjunction with other clinical and laboratory data obtained by your doctor, decisions regarding your treatment and care may be simplified. You may discontinue testing at any time.
The costs associated with the Mesomark blood test may not be covered under health insurance, therefore, you may be required to pay all or part of the costs out of pocket. It is recommended that you check with your insurance carrier to determine whether coverage is available under your policy.
Bello kamorudeen.http://www.mesotheliomacorner.blogspot.com
However, the ability to diagnose the disease at an earlier time would certainly result in a better prognosis for mesothelioma patients. That ability is now present in the form of a mesothelioma blood test known as Mesomark. Developed by Fujirebio Diagnostics Inc. of Malvern, Pennsylvania, a leader in the field of oncology testing, the test measures the amount of a particular biomarker in human serum.
The test was first released in Australia in March 2005 and distribution expanded to Europe just a few months later. Food and Drug Administration approval for the blood test was received nearly two years later in January 2007.
Testing for Mesothelioma
Mesomark is an easily performed blood test that uses an enzyme-linked immunosorbent assay to measure the amount of Soluble Mesothelin-Related Peptides (SMRP) in human serum. SMRP is a biomarker that is produced by mesothelioma cells, and this biomarker may be elevated in the serum of patients who have mesothelioma. The detection of the biomarker through a blood test can help attain an early diagnosis, resulting in more treatment options and a better prognosis for patients.
Mesomark is what is referred to as an in-vitro test. In this test, the blood that is drawn from the patient is sent to a laboratory to measure the level of SMRP. This is performed by using monoclonal antibodies that are known to specifically bind to SMRP. Measuring the amount of bound antibodies in the blood indicates the amount of SMRP, and certain levels indicate the presence of mesothelioma. In addition to detecting the presence of mesothelioma in yet-to-be-diagnosed patients, the Mesomark blood test may also be used to monitor the success of treatments in patients who have already been diagnosed with the disease.
These tests will also help determine the next course of treatment.
The Mesomark blood test has NOT yet been approved for the early diagnosis of mesothelioma.
This test has been approved as a Humanitarian Use Device (HUD), meaning that physicians must follow certain procedures to qualify their patients for testing. Once the physician is certified, informational brochures will be sent to be distributed to each applicable patient.
Those wishing to take part in Mesomark testing will be asked to provide one or more samples of blood. The blood samples will then be sent to a national reference laboratory for testing. In conjunction with other clinical and laboratory data obtained by your doctor, decisions regarding your treatment and care may be simplified. You may discontinue testing at any time.
The costs associated with the Mesomark blood test may not be covered under health insurance, therefore, you may be required to pay all or part of the costs out of pocket. It is recommended that you check with your insurance carrier to determine whether coverage is available under your policy.
Bello kamorudeen.http://www.mesotheliomacorner.blogspot.com
Friday, August 6, 2010
Mesothelioma Lawyers and Mesothelioma Lawsuits- Do you need them?
Why File a Mesothelioma Lawsuit ?
Every year, thousands of people die or become ill due to the negligence of asbestos manufacturers. If this has happened to you or a loved one, you should look for a mesothelioma lawyer as soon as possible. You may have been powerless to prevent current medical problems, but you do have legal options. Hire a lawyer with extensive experience and knowledge of asbestos claims to help you receive compensation from those responsible.
Mesothelioma cancer, which is almost exclusively caused by asbestos exposure, and other asbestos-related illnesses are attributed to negligence of asbestos companies who knew about the associated health risks and decided not to tell employees or leak this information to the general public. As early as the 1920s asbestos companies were completely aware that their product not only causes harm to human health, but that it could also lead ultimately to the death of those exposed to the harmful asbestos mineral.
By the 1930s and '40s, medical evidence had clearly linked exposure to asbestos to the development of lung disease and deadly asbestos related cancers. Asbestos companies had been extensively warned of these dangers, but instead of choosing to use alternative substances (and many were available at the time), the industry chose huge profits over the preservation of human health. It is because of these unethical actions that asbestos manufacturers are held liable for the undue suffering they caused many people suffering from asbestos related disease.
As a result, those with mesothelioma have the right to seek compensation from the asbestos companies through the court system because of their criminal actions. Filing a Lawsuit against these companies that are responsible for your asbestos exposure will not only bring justice to the corrupt asbestos industry, it will also give you the necessary compensation for the costs, as well as pain and suffering, associated with asbestos-induced illness. The following include some of the expenses for which you can pursue compensation:
* Lost wages * Medical bills * Group support for you and your loved ones * Funeral expenses * Travel expenses relating to medical treatments * Expenses not covered by health insurance
A mesothelioma lawyer can review even add more expenses that could be covered under your lawsuit, as each case varies. Make sure to save all medical and financial records relating to your asbestos-induced illness for this purpose.
Aside from providing these sorts of documents and answering questions about your condition and how you may have been exposed to asbestos, you will not have to be involved with other stages of the case. Mesothelioma lawyers understand that their clients are far too ill and concerned with spending time with their families to deal with the details of filing a lawsuit or attending trial. For this reason, mesothelioma lawyers handle every aspect and detail of the case.
Types of Lawsuits
There are two types of lawsuits you may rightfully file in asbestos injury cases. If a family member has passed away from an asbestos-induced disease, you can file a wrongful death suit. In a personal injury claim, the individual suffering with an asbestos-related illness must be the one to file suit. Specific rights in these lawsuits depend on the county and state where the case is filed. Employees of companies who used asbestos are not the only individuals who have rights against asbestos companies.
Although the vast majority of cases are between employers and employees, other groups have rights as well. For example, if you have developed an asbestos-related disease because a spouse or family member worked for a company using asbestos, you may also have a case. Asbestos fibers readily attaches to and travels well on clothing and hair, making it easy to track home after working around the material.
Having a mesothelioma lawyer is essential to successfully file suit against a corporation in an asbestos-related case. Although you have the legal right to pursue compensation, the entity being sued also has the legal right to try to disprove your case, and this is why it is so important to hire an experienced mesothelioma attorney who has the knowledge and experience to bring justice to those responsible for your illness.
About the Author
Bello kamorudeen http://www.mesotheliomacorner.blogspot.com
Every year, thousands of people die or become ill due to the negligence of asbestos manufacturers. If this has happened to you or a loved one, you should look for a mesothelioma lawyer as soon as possible. You may have been powerless to prevent current medical problems, but you do have legal options. Hire a lawyer with extensive experience and knowledge of asbestos claims to help you receive compensation from those responsible.
Mesothelioma cancer, which is almost exclusively caused by asbestos exposure, and other asbestos-related illnesses are attributed to negligence of asbestos companies who knew about the associated health risks and decided not to tell employees or leak this information to the general public. As early as the 1920s asbestos companies were completely aware that their product not only causes harm to human health, but that it could also lead ultimately to the death of those exposed to the harmful asbestos mineral.
By the 1930s and '40s, medical evidence had clearly linked exposure to asbestos to the development of lung disease and deadly asbestos related cancers. Asbestos companies had been extensively warned of these dangers, but instead of choosing to use alternative substances (and many were available at the time), the industry chose huge profits over the preservation of human health. It is because of these unethical actions that asbestos manufacturers are held liable for the undue suffering they caused many people suffering from asbestos related disease.
As a result, those with mesothelioma have the right to seek compensation from the asbestos companies through the court system because of their criminal actions. Filing a Lawsuit against these companies that are responsible for your asbestos exposure will not only bring justice to the corrupt asbestos industry, it will also give you the necessary compensation for the costs, as well as pain and suffering, associated with asbestos-induced illness. The following include some of the expenses for which you can pursue compensation:
* Lost wages * Medical bills * Group support for you and your loved ones * Funeral expenses * Travel expenses relating to medical treatments * Expenses not covered by health insurance
A mesothelioma lawyer can review even add more expenses that could be covered under your lawsuit, as each case varies. Make sure to save all medical and financial records relating to your asbestos-induced illness for this purpose.
Aside from providing these sorts of documents and answering questions about your condition and how you may have been exposed to asbestos, you will not have to be involved with other stages of the case. Mesothelioma lawyers understand that their clients are far too ill and concerned with spending time with their families to deal with the details of filing a lawsuit or attending trial. For this reason, mesothelioma lawyers handle every aspect and detail of the case.
Types of Lawsuits
There are two types of lawsuits you may rightfully file in asbestos injury cases. If a family member has passed away from an asbestos-induced disease, you can file a wrongful death suit. In a personal injury claim, the individual suffering with an asbestos-related illness must be the one to file suit. Specific rights in these lawsuits depend on the county and state where the case is filed. Employees of companies who used asbestos are not the only individuals who have rights against asbestos companies.
Although the vast majority of cases are between employers and employees, other groups have rights as well. For example, if you have developed an asbestos-related disease because a spouse or family member worked for a company using asbestos, you may also have a case. Asbestos fibers readily attaches to and travels well on clothing and hair, making it easy to track home after working around the material.
Having a mesothelioma lawyer is essential to successfully file suit against a corporation in an asbestos-related case. Although you have the legal right to pursue compensation, the entity being sued also has the legal right to try to disprove your case, and this is why it is so important to hire an experienced mesothelioma attorney who has the knowledge and experience to bring justice to those responsible for your illness.
About the Author
Bello kamorudeen http://www.mesotheliomacorner.blogspot.com
Monday, August 2, 2010
Mesothelioma Life Expectancy-What determines It?
Medical science has tried to increase the life expectancy for mesothelioma patients for decades. Since there is presently no known definitive cure for mesothelioma, the goal of the presently available intensive treatment for mesothelioma patients is to help prolong their life expectancy or improve the patient's overall quality of life.
What are the factors that determine a Mesothelioma Patient's Life Expectancy? This type of cancer is a rare cancer caused by asbestos exposure. The life expectancy of a mesothelioma patient is affected by numerous factors including:
* Latency period - The asbestos fibers that cause mesothelioma over time can lay dormant in the body for up to 50 years before causing any significant symptom or sign in the patient. This long period of latency often results in a late diagnosis. Most of the time the diagnosis is not made until the tumor has reached an advanced stage, making mesothelioma treatment difficult and sometimes ineffective. Mesothelioma patients diagnosed in later stages will typically receive palliative treatments rather than curative, which serve to make the patient more comfortable and increase their quality of life rather than cure the disease.
* Age at the time of Diagnosis- Research has shown that the average age of a mesothelioma patient is 60. If fact, more than 75 percent of mesothelioma cases diagnosed in the United States occur in men age 55 or older. However, some researchers believe the average age is dropping due to the influx of cases from secondary exposure. When an older person develops mesothelioma cancer, the presence of other health- age related problems may lead to certain challenges during treatment as their treatment might require modifications. These might include heart disease, additional lung ailments, and high blood pressure. Advanced age and the presence of other diseases can significantly affect and reduce patient's life span.
* The Type of Mesothelioma - There are three common types of mesothelioma that mesothelioma victims usually develop. The commonest form is pleural mesothelioma, which affects the lining of the lungs. Other forms of the disease include peritoneal and pericardial mesothelioma, which affect the lining of the abdomen and heart. Since pleural mesothelioma affects the most mesothelioma patients, more knowledge and research about this form of the cancer is available to utilize when detailing a treatment plan, often making the life expectancy for pleural mesothelioma patients longer.
* Smoking - Smoking greatly decreases the life span of people diagnosed with mesothelioma. Anyone diagnosed with mesothelioma should quit smoking immediately. Improving Life Expectancy
Those dedicated to researching mesothelioma are constantly testing new ways to improve the life expectancy of patients with the disease. This is carried out mainly through clinical trials, which test new drugs and treatments. Many promising alternatives to traditional treatments have been developed from clinical trials and patients often benefit from participating. Tests for early detection of mesothelioma are also being developed, which may result in more effective treatment of the disease.
The life expectancy of mesothelioma patients can also be affected by treatment. Mesothelioma patients may elect to undergo treatment to combat the disease, remove the cancer and kill cancerous cells. A doctor will make treatment recommendations based on a series of factors. Surgery, chemotherapy and radiotherapy are the most common mesothelioma treatment options for patients.
Bello kamorudeen http://www.mesotheliomacorner.blogspot.com
What are the factors that determine a Mesothelioma Patient's Life Expectancy? This type of cancer is a rare cancer caused by asbestos exposure. The life expectancy of a mesothelioma patient is affected by numerous factors including:
* Latency period - The asbestos fibers that cause mesothelioma over time can lay dormant in the body for up to 50 years before causing any significant symptom or sign in the patient. This long period of latency often results in a late diagnosis. Most of the time the diagnosis is not made until the tumor has reached an advanced stage, making mesothelioma treatment difficult and sometimes ineffective. Mesothelioma patients diagnosed in later stages will typically receive palliative treatments rather than curative, which serve to make the patient more comfortable and increase their quality of life rather than cure the disease.
* Age at the time of Diagnosis- Research has shown that the average age of a mesothelioma patient is 60. If fact, more than 75 percent of mesothelioma cases diagnosed in the United States occur in men age 55 or older. However, some researchers believe the average age is dropping due to the influx of cases from secondary exposure. When an older person develops mesothelioma cancer, the presence of other health- age related problems may lead to certain challenges during treatment as their treatment might require modifications. These might include heart disease, additional lung ailments, and high blood pressure. Advanced age and the presence of other diseases can significantly affect and reduce patient's life span.
* The Type of Mesothelioma - There are three common types of mesothelioma that mesothelioma victims usually develop. The commonest form is pleural mesothelioma, which affects the lining of the lungs. Other forms of the disease include peritoneal and pericardial mesothelioma, which affect the lining of the abdomen and heart. Since pleural mesothelioma affects the most mesothelioma patients, more knowledge and research about this form of the cancer is available to utilize when detailing a treatment plan, often making the life expectancy for pleural mesothelioma patients longer.
* Smoking - Smoking greatly decreases the life span of people diagnosed with mesothelioma. Anyone diagnosed with mesothelioma should quit smoking immediately. Improving Life Expectancy
Those dedicated to researching mesothelioma are constantly testing new ways to improve the life expectancy of patients with the disease. This is carried out mainly through clinical trials, which test new drugs and treatments. Many promising alternatives to traditional treatments have been developed from clinical trials and patients often benefit from participating. Tests for early detection of mesothelioma are also being developed, which may result in more effective treatment of the disease.
The life expectancy of mesothelioma patients can also be affected by treatment. Mesothelioma patients may elect to undergo treatment to combat the disease, remove the cancer and kill cancerous cells. A doctor will make treatment recommendations based on a series of factors. Surgery, chemotherapy and radiotherapy are the most common mesothelioma treatment options for patients.
Bello kamorudeen http://www.mesotheliomacorner.blogspot.com
Tuesday, July 27, 2010
Malignant Sarcomatoid Mesothelioma-What Is This?
In histological terms, there are four different types of mesothelioma: sarcomatoid, epithelial, biphasic, and desmoplastic (a variant of sarcomatoid).In medical terms, the term histopathology refers to the microscopic examination of cellular tissue to gain insight into the manifestations of various diseases.
Malignant sarcomatoid mesothelioma is the least common of the four cellular types. It accounts for approximately 7 to 20 percent of cases. When viewed under a microscope,the malignant cells appear as elongated spindle-shaped cells that are irregularly shaped and often overlap one another.
Desmoplastic mesothelioma is considered a variant of sarcomatoid mesothelioma. This form is likely the most difficult of all mesotheliomas to diagnose. When desmoplastic mesothelioma invades or metastasizes, the cells can appear very bland and can be misdiagnosed as benign fibrous tissue. Medical experts say this form should not be diagnosed with a needle core biopsy.
It's important to know that malignant sarcomatoid mesothelioma is sometimes difficult to diagnose on the basis of histological methods. For example, cells of another type of cancer called pulmonary sarcomatoid carcinoma are very similar in appearance (as well as other characteristics) to malignant sarcomatoid mesothelioma. For this reason, if you are diagnosed with cancer and you know that you have been exposed to asbestos at some time in the past, obtaining a second diagnostic opinion may be important. Different types of cancer vary widely in terms of prognosis and treatment options, and if misdiagnosed, patients may not receive the most appropriate treatment for their cancer.
Treatment and Prognosis
Each of the four cellular forms of mesothelioma is generally treated in the same way. Treatment is not based on the specific type of cells involved, but instead on the location of tumors and the stage of the cancer. Each type of cancer responds to treatment very differently. In general, patients with malignant sarcomatoid mesothelioma have a poorer prognosis than patients with the epithelioid type , as sarcomatoid cancers are more aggressive and more resistant to treatment. Unfortunately, the general prognosis for all the different types is usually poor, and the difference in prognosis between sarcomatoid, epithelioid, biphasic and desmoplastic cancers may amount to as little as a few months.
Biopsy and Histopathology
Patients undergoing medical evaluation to ascertain a diagnosis of mesothelioma will also have to undergo a variety of medical tests to determine the location and nature of the cancer.
- Biopsy: This involves removal of samples of suspected cancer cells from several locations in the tumor site which are taken to the laboratory for proper evaluation to determine what type of cells they are and whether the cells are malignant.
The biopsy samples are tested in the laboratory under the principles of histopathology in two ways: - They are viewed under a microscope to determine their general appearance. - The cells are also tested for the presence of oncoproteins and molecules that are specific to certain type of cancer cells.
When viewed under a microscope, mesothelioma cells and other types of cancer cells have different types of appearance and different shapes when compared to normal healthy cells. Further tests that evaluate the types of proteins present on the surface of the cells are needed to determine the exact nature of the cells.
When mesothelial cells become malignant, they begin to produce different types of proteins and some of these are present on the surface of the cells. Examining the types of surface proteins allows a histologist to determine if the cells are malignant mesothelioma, another type of cancer, or healthy cells. The application of histochemistry in the diagnosis of mesotheliomas is primarily to differentiate epithelial mesotheliomas from mucin-producing adenocarcinoma.
About the Author
Bello Kamorudeen http:www.mesotheliomacorner.blogspot.com
Malignant sarcomatoid mesothelioma is the least common of the four cellular types. It accounts for approximately 7 to 20 percent of cases. When viewed under a microscope,the malignant cells appear as elongated spindle-shaped cells that are irregularly shaped and often overlap one another.
Desmoplastic mesothelioma is considered a variant of sarcomatoid mesothelioma. This form is likely the most difficult of all mesotheliomas to diagnose. When desmoplastic mesothelioma invades or metastasizes, the cells can appear very bland and can be misdiagnosed as benign fibrous tissue. Medical experts say this form should not be diagnosed with a needle core biopsy.
It's important to know that malignant sarcomatoid mesothelioma is sometimes difficult to diagnose on the basis of histological methods. For example, cells of another type of cancer called pulmonary sarcomatoid carcinoma are very similar in appearance (as well as other characteristics) to malignant sarcomatoid mesothelioma. For this reason, if you are diagnosed with cancer and you know that you have been exposed to asbestos at some time in the past, obtaining a second diagnostic opinion may be important. Different types of cancer vary widely in terms of prognosis and treatment options, and if misdiagnosed, patients may not receive the most appropriate treatment for their cancer.
Treatment and Prognosis
Each of the four cellular forms of mesothelioma is generally treated in the same way. Treatment is not based on the specific type of cells involved, but instead on the location of tumors and the stage of the cancer. Each type of cancer responds to treatment very differently. In general, patients with malignant sarcomatoid mesothelioma have a poorer prognosis than patients with the epithelioid type , as sarcomatoid cancers are more aggressive and more resistant to treatment. Unfortunately, the general prognosis for all the different types is usually poor, and the difference in prognosis between sarcomatoid, epithelioid, biphasic and desmoplastic cancers may amount to as little as a few months.
Biopsy and Histopathology
Patients undergoing medical evaluation to ascertain a diagnosis of mesothelioma will also have to undergo a variety of medical tests to determine the location and nature of the cancer.
- Biopsy: This involves removal of samples of suspected cancer cells from several locations in the tumor site which are taken to the laboratory for proper evaluation to determine what type of cells they are and whether the cells are malignant.
The biopsy samples are tested in the laboratory under the principles of histopathology in two ways: - They are viewed under a microscope to determine their general appearance. - The cells are also tested for the presence of oncoproteins and molecules that are specific to certain type of cancer cells.
When viewed under a microscope, mesothelioma cells and other types of cancer cells have different types of appearance and different shapes when compared to normal healthy cells. Further tests that evaluate the types of proteins present on the surface of the cells are needed to determine the exact nature of the cells.
When mesothelial cells become malignant, they begin to produce different types of proteins and some of these are present on the surface of the cells. Examining the types of surface proteins allows a histologist to determine if the cells are malignant mesothelioma, another type of cancer, or healthy cells. The application of histochemistry in the diagnosis of mesotheliomas is primarily to differentiate epithelial mesotheliomas from mucin-producing adenocarcinoma.
About the Author
Bello Kamorudeen http:www.mesotheliomacorner.blogspot.com
Thursday, July 22, 2010
Mesothelioma Chemotherapy - 5 Commonly Asked Mesothelioma Chemotherapy Questions
Mesothelioma patients usually have some questions that they want answers for when they want to commence on Chemotherapy. These include:
1. What is chemotherapy for mesothelioma? Chemotherapy involves one or more anti-cancer drugs taken either orally in pill form, or intravenously, or, in the case of pleural mesothelioma, injected directly into the lungs. These drugs inhibit the growth of cancerous cells, but they also damage normal healthy cells as well leading to the development of side effects.
2. What are the common side effects of mesothelioma chemotherapy? Side effects are very common with the use of many Chemotherapy agents. The commonly seen side effects include:
* hair loss * nausea * vomiting * diarrhea * constipation * anemia * hemorrhaging
Chemotherapy also causes many complicated side effects within the cancerous growth. It is not uncommon in mesothelioma cases to have secondary neoplasms, which are cancerous offshoots of the original tumor that have redirected their growth due to the introduction of anti-cancer drugs.
3. What are the other risks of chemotherapy? Furthermore, chemotherapy often increases the chances of toxic reactions in the blood, liver, and kidneys, contributing to the potential fatal nature of chemotherapy treatment. Because chemotherapy suppresses the immune system by decreasing antibodies in the bloodstream, patients undergoing chemotherapy are vulnerable to having common infections and illnesses. Other complications are mouth sores which, in combination with the overwhelming nausea and intestinal discomfort caused by chemotherapy, results in many patients failing to eat a healthy diet.
4. What can you do if chemotherapy does not work? If you suffer from mesothelioma and chemotherapy has failed you, then you should consult with an attorney experienced in handling asbestos-related litigation. You have a right to pursue legal action to seek justice from those who wronged you. Don't delay, for the laws in your state limit the amount of time you have to collect damages, and these statutes of limitations can end your case before it can begin. Contact a lawyer today.
5. Does chemotherapy work well on mesothelioma? Chemotherapy does not result in a cure for mesothelioma as the cancer is usually too advanced at the time of diagnosis. Newer chemotherapy agents however are very useful in providing symptomatic relief and prolonging the life span of patients especially when used in combination with other modalities of treatment like surgery and radiotherapy.
Bello Kamorudeen.http://www.mesotheliomacorner.blogspot.com
1. What is chemotherapy for mesothelioma? Chemotherapy involves one or more anti-cancer drugs taken either orally in pill form, or intravenously, or, in the case of pleural mesothelioma, injected directly into the lungs. These drugs inhibit the growth of cancerous cells, but they also damage normal healthy cells as well leading to the development of side effects.
2. What are the common side effects of mesothelioma chemotherapy? Side effects are very common with the use of many Chemotherapy agents. The commonly seen side effects include:
* hair loss * nausea * vomiting * diarrhea * constipation * anemia * hemorrhaging
Chemotherapy also causes many complicated side effects within the cancerous growth. It is not uncommon in mesothelioma cases to have secondary neoplasms, which are cancerous offshoots of the original tumor that have redirected their growth due to the introduction of anti-cancer drugs.
3. What are the other risks of chemotherapy? Furthermore, chemotherapy often increases the chances of toxic reactions in the blood, liver, and kidneys, contributing to the potential fatal nature of chemotherapy treatment. Because chemotherapy suppresses the immune system by decreasing antibodies in the bloodstream, patients undergoing chemotherapy are vulnerable to having common infections and illnesses. Other complications are mouth sores which, in combination with the overwhelming nausea and intestinal discomfort caused by chemotherapy, results in many patients failing to eat a healthy diet.
4. What can you do if chemotherapy does not work? If you suffer from mesothelioma and chemotherapy has failed you, then you should consult with an attorney experienced in handling asbestos-related litigation. You have a right to pursue legal action to seek justice from those who wronged you. Don't delay, for the laws in your state limit the amount of time you have to collect damages, and these statutes of limitations can end your case before it can begin. Contact a lawyer today.
5. Does chemotherapy work well on mesothelioma? Chemotherapy does not result in a cure for mesothelioma as the cancer is usually too advanced at the time of diagnosis. Newer chemotherapy agents however are very useful in providing symptomatic relief and prolonging the life span of patients especially when used in combination with other modalities of treatment like surgery and radiotherapy.
Bello Kamorudeen.http://www.mesotheliomacorner.blogspot.com
Sunday, July 18, 2010
Mesothelioma Chemotherapy - What Are the Six Commonly Used Chemotherapy Agents?
Mesothelioma cancer, can be treated by the use of anti cancer drug therapies. These anti cancer drugs act by inhibiting tumor growth through the blocking of cell division and multiplication. This mode of action also unfortunately affects other rapidly replicating cells in the body, cells of the hair and the lining of the intestine are particularly vulnerable, thus leading to the common side effects of anti cancer drugs like hair loss and nausea.
Mesothelioma is notoriously resistant to common anti cancer chemotherapy as result of some reasons. The cancer takes a long time to mature and show symptoms, by the time these symptoms appear the tumor will be well formed with a lot of layers of dead cells that the anti cancer drugs will find it difficult to penetrate, and also by the time a diagnosis of mesothelioma is made, most victims have but a short time left to live so the drugs do not have enough time to exert their maximal effect.
New drugs that have been designed to overcome these challenges and have fewer and lesser side effects include:
Alimta (Pemetrexed)
Alimta was approved by The Food and Drug Administration in February 2004 as a new anti cancer drug for the treatment of mesothelioma. Its mode of action is by inhibiting the creation of thymidine and purine , two enzymes that are vital to cell growth. This stops the mesothelioma cancer cells from multiplying at a very fast rate. Its side effects include nausea and vomiting, diarrhea, fatigue, mouth sores and low blood counts. Patients are usually placed on vitamin B12 and folic acid supplements to reduce the severity of the side effects.
Cisplatin
This is a platinum-based chemotherapy drug that prevents the reproduction of DNA and is used to treat a number of different cancers including mesothelioma. The FDA approved it in 1978 to treat a number of cancers, and has proved somewhat effective on mesothelioma. Cisplatin however has some very serious side effects which inlude ear damage{ototoxicity} leading to hearing loss, kidney damage, nerve damage, and nausea, and so some oncologist are very reluctant to prescribe this drug to patients.
Tomudex (Raltitrexed)
This drug prevents cancer cells from replicating the DNA that is needed for multiplication and spread of cancer. This drug can be used as a monotherapy or in combination with onconase.
Vinorelbine
This anticancer drug was initially approved by the FDA in 1994 for the treatment of small lung cancer and breast cancer, but recent studies have shown that it could also be effective against mesothelioma, and the drug has little side effect profile. It can also be used in combination with some other chemotherapy drugs.
Onconase (Ranpirnase/P-30 Protein)
Onconase is a chemical taken from the eggs of the leopard frog that blocks protein synthesis which leads to blockage of tumor cell division and growth. It has shown promise as becoming one of the more effective drugs for treating cancer, as survival rates for one and two years are 34.4% and 21.6 respectively, as opposed to six to eight months without treatment.
Veglin
This is an anticancer chemotherapy drug that blocks the growth of tumors in people suffering from lymphoma, Kaposi's sarcoma, and colon and lung cancers. Many oncologists believe that it could be effective in fighting mesothelioma, as Veglin inhibits vascular endothelial growth factor (VEGF), a substance that is usually found in very high concentrations in mesothelioma patients. VEGF helps tumors grow new blood vessels which help to supply nutrients to the new tumor cells. This drug inhibits this process thus starving the new cancer cells of their much needed nutrients, leading to their ultimate death
Bello Kamorudeen.http://www.mesotheliomacorner.blogspot.com
Mesothelioma is notoriously resistant to common anti cancer chemotherapy as result of some reasons. The cancer takes a long time to mature and show symptoms, by the time these symptoms appear the tumor will be well formed with a lot of layers of dead cells that the anti cancer drugs will find it difficult to penetrate, and also by the time a diagnosis of mesothelioma is made, most victims have but a short time left to live so the drugs do not have enough time to exert their maximal effect.
New drugs that have been designed to overcome these challenges and have fewer and lesser side effects include:
Alimta (Pemetrexed)
Alimta was approved by The Food and Drug Administration in February 2004 as a new anti cancer drug for the treatment of mesothelioma. Its mode of action is by inhibiting the creation of thymidine and purine , two enzymes that are vital to cell growth. This stops the mesothelioma cancer cells from multiplying at a very fast rate. Its side effects include nausea and vomiting, diarrhea, fatigue, mouth sores and low blood counts. Patients are usually placed on vitamin B12 and folic acid supplements to reduce the severity of the side effects.
Cisplatin
This is a platinum-based chemotherapy drug that prevents the reproduction of DNA and is used to treat a number of different cancers including mesothelioma. The FDA approved it in 1978 to treat a number of cancers, and has proved somewhat effective on mesothelioma. Cisplatin however has some very serious side effects which inlude ear damage{ototoxicity} leading to hearing loss, kidney damage, nerve damage, and nausea, and so some oncologist are very reluctant to prescribe this drug to patients.
Tomudex (Raltitrexed)
This drug prevents cancer cells from replicating the DNA that is needed for multiplication and spread of cancer. This drug can be used as a monotherapy or in combination with onconase.
Vinorelbine
This anticancer drug was initially approved by the FDA in 1994 for the treatment of small lung cancer and breast cancer, but recent studies have shown that it could also be effective against mesothelioma, and the drug has little side effect profile. It can also be used in combination with some other chemotherapy drugs.
Onconase (Ranpirnase/P-30 Protein)
Onconase is a chemical taken from the eggs of the leopard frog that blocks protein synthesis which leads to blockage of tumor cell division and growth. It has shown promise as becoming one of the more effective drugs for treating cancer, as survival rates for one and two years are 34.4% and 21.6 respectively, as opposed to six to eight months without treatment.
Veglin
This is an anticancer chemotherapy drug that blocks the growth of tumors in people suffering from lymphoma, Kaposi's sarcoma, and colon and lung cancers. Many oncologists believe that it could be effective in fighting mesothelioma, as Veglin inhibits vascular endothelial growth factor (VEGF), a substance that is usually found in very high concentrations in mesothelioma patients. VEGF helps tumors grow new blood vessels which help to supply nutrients to the new tumor cells. This drug inhibits this process thus starving the new cancer cells of their much needed nutrients, leading to their ultimate death
Bello Kamorudeen.http://www.mesotheliomacorner.blogspot.com
Wednesday, July 14, 2010
Two Important Steps That Will Help You to Cope With a Diagnosis of Mesothelioma
Receiving a diagnosis of mesothelioma is undoubtedly one of the most devastating and harrowing experiences one can pass through in life, it is like receiving a certain death sentence. All patients will pass through the classical stages of grief, the initial shock followed by denial, then anger, then depression, and finally acceptance of the grim reality of the terminal disease.
This mix of powerful emotions can overwhelm even those that claim to be very strong individuals. This disease often leaves its victims in a very fragile state of mind.
Even the most compassionate and understanding people can be frustrated by the mortality of mesothelioma, and they can become worn out emotionally very quickly if they do not take steps to help them cope with the disease. Mesothelioma diagnosis is a tragic and devastating revelation, and these are some steps that you can take to help you cope with the disease.
1-Try and overcome the fear and sorrow that usually comes with the diagnosis of a terminal illness. Reach out to your friends, strengthen your religious faith, locate and interact with other victims of the disease to learn how they are coping and share experiences with each other. Also draw strength from within your innate powerful resources that can only manifest when you are facing an almost impossible situation like this.
Face this certain mortality with dignity and poise. Fear and hopelessness will only rob you of what little time you have left, and hinder any positive decisions you might have to make.
2-You still control your life, make a choice to make a difference. Try and pursue legal action against those who knowingly put you at risk of developing this cancer, they purposefully exposed you to asbestos exposure to maximize profit and they must pay for their actions. This will serve justice to a callous and very selfish industry.
Also the monetary compensation you will get will give you the assurance that even after you might have passed away, your family will not have to suffer financially. This will also help you to face inevitable mortality with a lot of courage. So contact a mesothelioma Lawyer as soon as possible.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
This mix of powerful emotions can overwhelm even those that claim to be very strong individuals. This disease often leaves its victims in a very fragile state of mind.
Even the most compassionate and understanding people can be frustrated by the mortality of mesothelioma, and they can become worn out emotionally very quickly if they do not take steps to help them cope with the disease. Mesothelioma diagnosis is a tragic and devastating revelation, and these are some steps that you can take to help you cope with the disease.
1-Try and overcome the fear and sorrow that usually comes with the diagnosis of a terminal illness. Reach out to your friends, strengthen your religious faith, locate and interact with other victims of the disease to learn how they are coping and share experiences with each other. Also draw strength from within your innate powerful resources that can only manifest when you are facing an almost impossible situation like this.
Face this certain mortality with dignity and poise. Fear and hopelessness will only rob you of what little time you have left, and hinder any positive decisions you might have to make.
2-You still control your life, make a choice to make a difference. Try and pursue legal action against those who knowingly put you at risk of developing this cancer, they purposefully exposed you to asbestos exposure to maximize profit and they must pay for their actions. This will serve justice to a callous and very selfish industry.
Also the monetary compensation you will get will give you the assurance that even after you might have passed away, your family will not have to suffer financially. This will also help you to face inevitable mortality with a lot of courage. So contact a mesothelioma Lawyer as soon as possible.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Saturday, July 10, 2010
Alarming Mesothelioma Statistics For You to Know
Mesothelioma is not a very common disease with about 2000-3000 new cases seen in the US every year.
-There was a gradual increase in the number of cases of newly diagnosed mesothelioma victims in the United States from the 1970's to the 1990's after which the number became fairly constant. After the year 2000 and beyond the number has likely been on the decrease.
-Mesothelioma is more common in men. It is four times commoner in men than in women.
-The number of new Mesothelioma cases is still increasing in European countries.
-Mesothelioma commonly affects people over the age of 55 years, it is very rare to find Mesothelioma in people under the age of 55 years and its incidence increases with age, about 90% of people diagnosed with Mesothelioma are over the age of 65 years.
-This cancer is commoner in Caucasians and Hispanics than in African Americans or in Asian Americans.
-The mean lifespan of the victims of this deadly cancer is between four to eighteen months. About nine to ten percent of mesothelioma victims live up to five years after diagnosis. The lifespan of individual cases depend on many factors including the stage and the degree of spread of the tumor at diagnosis, the age of the victim at diagnosis, general state of health, and some other factors.
-It is however important to note that most of these survival data were collected from patients diagnosed and treated years ago , it is most likely that these figures might have improved by now with more victims living longer after diagnosis.
-Finally it is important to also note that these figures are just a guide and they do not determine your own outcome of the disease. So many other individual factors come to play to determine your own actual outcome, you should discuss with your oncologist to know how best these figures apply to you.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
-There was a gradual increase in the number of cases of newly diagnosed mesothelioma victims in the United States from the 1970's to the 1990's after which the number became fairly constant. After the year 2000 and beyond the number has likely been on the decrease.
-Mesothelioma is more common in men. It is four times commoner in men than in women.
-The number of new Mesothelioma cases is still increasing in European countries.
-Mesothelioma commonly affects people over the age of 55 years, it is very rare to find Mesothelioma in people under the age of 55 years and its incidence increases with age, about 90% of people diagnosed with Mesothelioma are over the age of 65 years.
-This cancer is commoner in Caucasians and Hispanics than in African Americans or in Asian Americans.
-The mean lifespan of the victims of this deadly cancer is between four to eighteen months. About nine to ten percent of mesothelioma victims live up to five years after diagnosis. The lifespan of individual cases depend on many factors including the stage and the degree of spread of the tumor at diagnosis, the age of the victim at diagnosis, general state of health, and some other factors.
-It is however important to note that most of these survival data were collected from patients diagnosed and treated years ago , it is most likely that these figures might have improved by now with more victims living longer after diagnosis.
-Finally it is important to also note that these figures are just a guide and they do not determine your own outcome of the disease. So many other individual factors come to play to determine your own actual outcome, you should discuss with your oncologist to know how best these figures apply to you.
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Tuesday, July 6, 2010
Mesothelioma Prevention - Three Main Ways To Prevent Mesothelioma
The main way by which mesothelioma is prevented is by reducing and limiting exposure to asbestos at home, at work and at public places. These three measures help to prevent and reduce exposure to asbestos fibers.
1. Jobs that have high risk of exposure to asbestos include mining, factory workers, insulation manufacturers, railroad and automotive workers, ship builders, gas mask manufacturers, and construction workers, particularly those involved with insulation. People that work in any of these sites should always put on protective gowns, and they fully adopt and abide by all the safety work procedures and practices in their place of work.
2. Old houses might have asbestos containing insulation materials and people living in them could also be at risk of exposure to asbestos. If you live in an old house you might need to get a knowledgeable expert to determine the level of asbestos in your home, so that you can know if you are at risk from asbestos. Generally however asbestos in buildings might not pose much danger if they are in good condition, it is only when they are tampered with when you attempt to remove them that they might actually be released into the air, so it is better you live them alone.
If in any case you decide to remove asbestos from your home you must get a qualified contractor to remove them for you to prevent contamination of your home further. Never attempt to remove the asbestos containing materials yourself.
3. Some commercial and public buildings especially come schools also contain asbestos. These buildings could expose people to asbestos especially if they are damaged and when they start deteriorating gradually over time. Federal Laws require that schools and public buildings should inspect their asbestos containing buildings regularly and have a plan for managing them
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
1. Jobs that have high risk of exposure to asbestos include mining, factory workers, insulation manufacturers, railroad and automotive workers, ship builders, gas mask manufacturers, and construction workers, particularly those involved with insulation. People that work in any of these sites should always put on protective gowns, and they fully adopt and abide by all the safety work procedures and practices in their place of work.
2. Old houses might have asbestos containing insulation materials and people living in them could also be at risk of exposure to asbestos. If you live in an old house you might need to get a knowledgeable expert to determine the level of asbestos in your home, so that you can know if you are at risk from asbestos. Generally however asbestos in buildings might not pose much danger if they are in good condition, it is only when they are tampered with when you attempt to remove them that they might actually be released into the air, so it is better you live them alone.
If in any case you decide to remove asbestos from your home you must get a qualified contractor to remove them for you to prevent contamination of your home further. Never attempt to remove the asbestos containing materials yourself.
3. Some commercial and public buildings especially come schools also contain asbestos. These buildings could expose people to asbestos especially if they are damaged and when they start deteriorating gradually over time. Federal Laws require that schools and public buildings should inspect their asbestos containing buildings regularly and have a plan for managing them
Bello Kamorudeen. http://www.mesotheliomacorner.blogspot.com
Friday, July 2, 2010
Causes of Mesothelioma - An Insight Into the Likely Causes of Mesothelioma
Mesothelioma is a very aggressive and rare cancer that is difficult to diagnose and that is also highly resistant to treatment. Around 2000-3000 new cases of malignant mesothelioma are seen every year in the US, and these figures are expected to rise over the next decade.
What causes mesothelioma?
There is extensive and undeniable medical evidence that mesothelioma is caused by exposure to asbestos fibers. There is no other known cause.
Asbestos is a naturally occurring fibrous material that was widely used in industrial, commercial and domestic products throughout the 20th century. It was particularly popular because of its durability, fire resistant and insulating properties. It was used in several thousand different manufactured asbestos products. These included construction materials, household appliances and brake linings, the use was so widespread that millions of Americans were unknowingly exposed to the toxic material, which now leads to the development of mesothelioma amongst million of Americans.
Most of the companies that manufactured these asbestos contaminated products were aware of the danger of asbestos, but still preferred to put millions at risk to make huge profits.
However today, as more cases are being diagnosed and they are seeking for legal compensation, these companies are being ordered to pay compensations to patients affected by asbestos.
How does asbestos cause mesothelioma?
Internal organs and body cavities are lined by a thin tissue called mesothelium. This lining lines the lungs {pleura} and it also lines the heart sac {pericardium} and abdominal cavity {peritoneum}.
This mesothelial tissue offers protection and support for the internal organs and body cavities. It also provides lubrication to help organ function properly and be in good health.
Mesothelioma affects this lining of various organs and body cavities, mostly the pleura, pericardium, and peritoneum. Occasionally and rarely, the cancer may affect the lining of the testicles, called the tunica vaginalis.
Although the actual mechanism by which asbestos causes cancer is not known, there are about four different theories to explain this:
1-Asbestos causes irritation and inflammation of mesothelial cells, which results in irreversible scarring, cellular damage, and eventually cancer
2- Asbestos fibers enter cells and disrupt the function of cellular structures that are essential for normal cell division, causing cellular changes that lead to cancer.
3-Asbestos causes the production of free radicals. These molecules damage DNA, and cause cells to mutate and become cancerous.
4-The presence of asbestos causes cells to produce oncoproteins. These molecules cause mesothelial cells to ignore normal cellular division restraints, and this can lead to the development of cancer.
The common underlying pathophysiology in each of these theories is that asbestos cause's cellular damage mainly by causing the cells of the mesothelium to divide and multiply without restraint causing the formation of tumors. This uncontrolled division causes impairment of the normal function of the body organs and tissues.
Does Mesothelioma have other causes? Although research and medical evidence has not been able to directly prove any other cause of mesothelioma other than asbestos exposure, it is known however that smoking can aggravate a less serious asbestos related disease, such as asbestosis, and prompt formation of tumors and the onset of the cancer.
Also asbestos exposure and smoking have a synergistic effect that increases the risk of developing lung cancer by as much as 84 times or more. Thus people that have been exposed to asbestos for a prolonged period of time are advised to not to smoke.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
What causes mesothelioma?
There is extensive and undeniable medical evidence that mesothelioma is caused by exposure to asbestos fibers. There is no other known cause.
Asbestos is a naturally occurring fibrous material that was widely used in industrial, commercial and domestic products throughout the 20th century. It was particularly popular because of its durability, fire resistant and insulating properties. It was used in several thousand different manufactured asbestos products. These included construction materials, household appliances and brake linings, the use was so widespread that millions of Americans were unknowingly exposed to the toxic material, which now leads to the development of mesothelioma amongst million of Americans.
Most of the companies that manufactured these asbestos contaminated products were aware of the danger of asbestos, but still preferred to put millions at risk to make huge profits.
However today, as more cases are being diagnosed and they are seeking for legal compensation, these companies are being ordered to pay compensations to patients affected by asbestos.
How does asbestos cause mesothelioma?
Internal organs and body cavities are lined by a thin tissue called mesothelium. This lining lines the lungs {pleura} and it also lines the heart sac {pericardium} and abdominal cavity {peritoneum}.
This mesothelial tissue offers protection and support for the internal organs and body cavities. It also provides lubrication to help organ function properly and be in good health.
Mesothelioma affects this lining of various organs and body cavities, mostly the pleura, pericardium, and peritoneum. Occasionally and rarely, the cancer may affect the lining of the testicles, called the tunica vaginalis.
Although the actual mechanism by which asbestos causes cancer is not known, there are about four different theories to explain this:
1-Asbestos causes irritation and inflammation of mesothelial cells, which results in irreversible scarring, cellular damage, and eventually cancer
2- Asbestos fibers enter cells and disrupt the function of cellular structures that are essential for normal cell division, causing cellular changes that lead to cancer.
3-Asbestos causes the production of free radicals. These molecules damage DNA, and cause cells to mutate and become cancerous.
4-The presence of asbestos causes cells to produce oncoproteins. These molecules cause mesothelial cells to ignore normal cellular division restraints, and this can lead to the development of cancer.
The common underlying pathophysiology in each of these theories is that asbestos cause's cellular damage mainly by causing the cells of the mesothelium to divide and multiply without restraint causing the formation of tumors. This uncontrolled division causes impairment of the normal function of the body organs and tissues.
Does Mesothelioma have other causes? Although research and medical evidence has not been able to directly prove any other cause of mesothelioma other than asbestos exposure, it is known however that smoking can aggravate a less serious asbestos related disease, such as asbestosis, and prompt formation of tumors and the onset of the cancer.
Also asbestos exposure and smoking have a synergistic effect that increases the risk of developing lung cancer by as much as 84 times or more. Thus people that have been exposed to asbestos for a prolonged period of time are advised to not to smoke.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
Monday, June 28, 2010
Pericardial Mesothelioma - Symptoms, Diagnosis, Treatment, Prognosis & Basic Facts For You to Know
Pericardial mesothelioma accounts for about half of all pericardial tumors and is extremely rare. This cancer accounts for about 6% of all mesothelioma cases, these tumors are typically diffused and tend to cover the whole heart.
Pericardial mesothelioma affects the pericardium which is the membrane made up of mesothelial cells that surrounds and protects the heart. This membrane has two layers: A} an outer layer called parietal pericardium B} an inner layer called the visceral pericardium {epicardium}
Cause
Unlike in the case of pleural mesothelioma, there is no clear link between this cancer and exposure to asbestos fibers, but a number of patients with pericardial mesothelioma have a history of exposure to asbestos.
Some schools of thought believe that it is the inhaled asbestos fibers in the lungs that travel via blood from the lungs to the heart, although this theory is not supported by conclusive evidence.
When asbestos fibers get lodged in the pericardium, the body is unable to excrete the asbestos fibers and they remain stuck in the pericardium. These fibers over a long period of time cause the pericardial cells to undergo changes that result into cancerous transformation.
The cancer cells divide without control and they eventually lead to the thickening of the pericardial membranes eventually causing development of the tumors. These changes lead to the accumulation of fluids in between the two layers which combined with the thickening of these layers result in the compression of the heart.
Symptoms
Most of the symptoms are caused by the accumulation of fluids and the thickening of the pericardial layer. The common symptoms are: A) Heart palpitations or irregular pulse (arrhythmias) B) Chest pain C) Murmurs (abnormal heart sounds) D) Cough E) Dyspnoea (shortness of breath) F) Fatigue H) Fever or night sweats I) Orthopnoea (breathlessness on lying down)
These symptoms are not specific for the cancer, making the clinical diagnosis very difficult.
Diagnosis
After getting a clinical diagnosis a series of tests can be done to locate the cancer and identify the cancer cells.
-MRI, Magnetic Resonance Imaging
This is useful in assessing and determining the extent of development of the cancer.
-Biopsy
This involves the removal of pericardium tissue or fluid for laboratory test to confirm the presence of mesothelioma cells.
-Chest x-ray
This helps to identify the tumor, there is a characteristic shape of the heart on the x-ray film when there is a tumor of the pericardium.
-Chest CT scan
This also helps to identify the tumor.
Treatment
Pericardial mesothelioma patients are not usually suitable for surgery, except in rare cases where the cancer is diagnosed very early and surgery may be done to remove small localized tumors.
This type of surgery is very risky because of the proximity of the heart.
Palliative treatment is often the only option for treating pericardial mesothelioma, this type of treatment is aimed at improving the patient's quality of life and reducing the severity of symptoms caused by the accumulation of fluid in the pericardium.
Fine needle aspiration may be done to drain the accumulated fluid surrounding the heart. Radiotherapy could also be used to shrink the tumor to alleviate the symptoms caused by the compression of the heart by the accumulating fluid. The proximity of the heart and lungs however makes this a very risky procedure.
Prognosis
The prognosis of this type of mesothelioma is very poor, about 50 -60% of all cases die within 6 months of diagnosis. Occasionally few patients survive for longer periods following treatment with partial surgical resection and radiotherapy.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
Pericardial mesothelioma affects the pericardium which is the membrane made up of mesothelial cells that surrounds and protects the heart. This membrane has two layers: A} an outer layer called parietal pericardium B} an inner layer called the visceral pericardium {epicardium}
Cause
Unlike in the case of pleural mesothelioma, there is no clear link between this cancer and exposure to asbestos fibers, but a number of patients with pericardial mesothelioma have a history of exposure to asbestos.
Some schools of thought believe that it is the inhaled asbestos fibers in the lungs that travel via blood from the lungs to the heart, although this theory is not supported by conclusive evidence.
When asbestos fibers get lodged in the pericardium, the body is unable to excrete the asbestos fibers and they remain stuck in the pericardium. These fibers over a long period of time cause the pericardial cells to undergo changes that result into cancerous transformation.
The cancer cells divide without control and they eventually lead to the thickening of the pericardial membranes eventually causing development of the tumors. These changes lead to the accumulation of fluids in between the two layers which combined with the thickening of these layers result in the compression of the heart.
Symptoms
Most of the symptoms are caused by the accumulation of fluids and the thickening of the pericardial layer. The common symptoms are: A) Heart palpitations or irregular pulse (arrhythmias) B) Chest pain C) Murmurs (abnormal heart sounds) D) Cough E) Dyspnoea (shortness of breath) F) Fatigue H) Fever or night sweats I) Orthopnoea (breathlessness on lying down)
These symptoms are not specific for the cancer, making the clinical diagnosis very difficult.
Diagnosis
After getting a clinical diagnosis a series of tests can be done to locate the cancer and identify the cancer cells.
-MRI, Magnetic Resonance Imaging
This is useful in assessing and determining the extent of development of the cancer.
-Biopsy
This involves the removal of pericardium tissue or fluid for laboratory test to confirm the presence of mesothelioma cells.
-Chest x-ray
This helps to identify the tumor, there is a characteristic shape of the heart on the x-ray film when there is a tumor of the pericardium.
-Chest CT scan
This also helps to identify the tumor.
Treatment
Pericardial mesothelioma patients are not usually suitable for surgery, except in rare cases where the cancer is diagnosed very early and surgery may be done to remove small localized tumors.
This type of surgery is very risky because of the proximity of the heart.
Palliative treatment is often the only option for treating pericardial mesothelioma, this type of treatment is aimed at improving the patient's quality of life and reducing the severity of symptoms caused by the accumulation of fluid in the pericardium.
Fine needle aspiration may be done to drain the accumulated fluid surrounding the heart. Radiotherapy could also be used to shrink the tumor to alleviate the symptoms caused by the compression of the heart by the accumulating fluid. The proximity of the heart and lungs however makes this a very risky procedure.
Prognosis
The prognosis of this type of mesothelioma is very poor, about 50 -60% of all cases die within 6 months of diagnosis. Occasionally few patients survive for longer periods following treatment with partial surgical resection and radiotherapy.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
Thursday, June 24, 2010
Mesothelioma Law Firm - How to Choose the Best One For You
The choice of the law firm to handle your mesothelioma lawsuit is a very important choice to make. You must choose a law firm that will suit your needs. You must bear in mind that mesothelioma lawsuits tend to drag over a long time and they can be very expensive.
The road to justice in most of these lawsuits is often not very smooth and getting your desired justice might not be that easy.
The law firm you hire must be able to deliver the main goal of the lawsuit which is to win the case for you. The firm you choose will determine whether or not you will get the compensation you deserve, so you will have to choose very well. The better your choice, the better your chances of winning the case. Your law firm must be able to get you the justice you desire, be sure to explore all the options before you, do not rush into signing a contract with just any one.
-A good law firm will not make the lawsuit a cumbersome and expensive task.
-When trying to hire a mesothelioma law firm you will be faced with two options, either you hire a big or a small law firm.
-The big law firm usually have longstanding experience in mesothelioma lawsuits, they would have been involved in many asbestos exposure related lawsuits. Most of the cases they take up against asbestos related industries have been on behalf of groups, so they might end up sidelining small individual cases like yours.
When these big law firms handle your case, your chances of getting individual attention is poor.
The amount of likely mesothelioma settlements in small cases like yours might not encourage the big law firms. Also the mass settlements these big law firms usually get from the asbestos industries will not benefit you very much.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
The road to justice in most of these lawsuits is often not very smooth and getting your desired justice might not be that easy.
The law firm you hire must be able to deliver the main goal of the lawsuit which is to win the case for you. The firm you choose will determine whether or not you will get the compensation you deserve, so you will have to choose very well. The better your choice, the better your chances of winning the case. Your law firm must be able to get you the justice you desire, be sure to explore all the options before you, do not rush into signing a contract with just any one.
-A good law firm will not make the lawsuit a cumbersome and expensive task.
-When trying to hire a mesothelioma law firm you will be faced with two options, either you hire a big or a small law firm.
-The big law firm usually have longstanding experience in mesothelioma lawsuits, they would have been involved in many asbestos exposure related lawsuits. Most of the cases they take up against asbestos related industries have been on behalf of groups, so they might end up sidelining small individual cases like yours.
When these big law firms handle your case, your chances of getting individual attention is poor.
The amount of likely mesothelioma settlements in small cases like yours might not encourage the big law firms. Also the mass settlements these big law firms usually get from the asbestos industries will not benefit you very much.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com
Sunday, June 20, 2010
Mesothelioma-Most Commonly Asked Questions
Mesothelioma is an uncommon cancer that affects primarily the mesothelium which is a protective sac covering most of the body's internal organs. Exposure to asbestos particles at the place of work has been strongly linked to the development of mesothelioma in most of the victims.
Some of the most frequently asked questions on mesothelioma are:
1- Is there any ongoing research to discover new treatments for mesothelioma?
Yes, there are new treatments that are being studied. The National Cancer Institute {NCI} is sponsoring clinical trials {research with people} which are designed to find new modes of treatment and also to discover better ways of using currently used treatments.
Most of these treatments are still undergoing clinical trials by doctors to find out whether the treatments are safe for patients and whether they are effective against the disease before they can be recommended for general use.
Mesothelioma victims can offer themselves for participation in these clinical trials as a treatment option. Information about clinical trials is available from the Cancer Information Service{CIS} at 1-800-4-Cancer.
2- How can Mesothelioma be treated?
The treatment of mesothelioma depends on, the location of the cancer,stage of the disease, and patients age and general health.
Treatment options include
a} Chemotherapy, b} Radiotherapy, c} Surgery.
These forms of treatment are sometimes combined.
- Chemotherapy: This involves the use of anticancer drugs to selectively destroy and kill the cancer cells in the body. Most of the anticancer drugs are administered intravenously. Ongoing research into possibility of direct administration of anticancer drugs into the chest or abdomen is currently being studied.
- Radiotherapy: This involves the use of high energy rays {radiation} to kill the cancer cells and debulk {shrink} tumors. The radiation is directed only at the affected area of the body to kill the cancer cells.
Radiation can be from an external machine placed outside the body {external radiation},or it could be form an internal source where the material releasing the radiation is placed inside the area of the body affected by cancer cells. It is placed with the use of thin plastic tubes.
- Surgery: This is a very common mode of treatment in treating mesothelioma. The surgeon may remove part of the lining of the chest and abdomen and some of the surrounding tissue. Sometimes an operation called pneumonectomy is done during which a whole lung is removed. Other forms of surgery involves the removal of part of the diaphragm, this is the muscular sheet separating the chest cavity from the abdominal cavity.
Some of the most frequently asked questions on mesothelioma are:
1- Is there any ongoing research to discover new treatments for mesothelioma?
Yes, there are new treatments that are being studied. The National Cancer Institute {NCI} is sponsoring clinical trials {research with people} which are designed to find new modes of treatment and also to discover better ways of using currently used treatments.
Most of these treatments are still undergoing clinical trials by doctors to find out whether the treatments are safe for patients and whether they are effective against the disease before they can be recommended for general use.
Mesothelioma victims can offer themselves for participation in these clinical trials as a treatment option. Information about clinical trials is available from the Cancer Information Service{CIS} at 1-800-4-Cancer.
2- How can Mesothelioma be treated?
The treatment of mesothelioma depends on, the location of the cancer,stage of the disease, and patients age and general health.
Treatment options include
a} Chemotherapy, b} Radiotherapy, c} Surgery.
These forms of treatment are sometimes combined.
- Chemotherapy: This involves the use of anticancer drugs to selectively destroy and kill the cancer cells in the body. Most of the anticancer drugs are administered intravenously. Ongoing research into possibility of direct administration of anticancer drugs into the chest or abdomen is currently being studied.
- Radiotherapy: This involves the use of high energy rays {radiation} to kill the cancer cells and debulk {shrink} tumors. The radiation is directed only at the affected area of the body to kill the cancer cells.
Radiation can be from an external machine placed outside the body {external radiation},or it could be form an internal source where the material releasing the radiation is placed inside the area of the body affected by cancer cells. It is placed with the use of thin plastic tubes.
- Surgery: This is a very common mode of treatment in treating mesothelioma. The surgeon may remove part of the lining of the chest and abdomen and some of the surrounding tissue. Sometimes an operation called pneumonectomy is done during which a whole lung is removed. Other forms of surgery involves the removal of part of the diaphragm, this is the muscular sheet separating the chest cavity from the abdominal cavity.
Wednesday, June 16, 2010
Mesothelioma - Support and Advise For the Mesothelioma Victims
Most people that develop mesothelioma have been exposed to asbestos in the past. Mesothelioma, a cancer of the mesothelium grows mainly in the lining of the lungs and abdomen and it takes decades for the symptoms of the cancer to surface. The main symptoms are chest pain and difficulty in breathing.
If you have worked with asbestos or materials containing asbestos, for example shipyard workers, insulation engineers, maintenance workers, building workers, you can develop mesothelioma. People working in other industries could also be exposed to asbestos without remembering the exposure. Also some people who were exposed to asbestos through washing and handling of clothes contaminated with asbestos and some people living close to asbestos industries may also develop mesothelioma.
Presently there is no known cure for mesothelioma, the treatments available only help to control the symptoms and improve quality of life of the victim. The type of treatment will be individualized and it depends on the stage of the cancer.
Help and Support Every mesothelioma case will need support and help, many find it hard difficult to accept the diagnosis, others feel bitter and angry. Every mesothelioma victim must have access both to information about the disease and to emotional support, including someone to talk to when they feel like. There are several specialist organizations that provide such help.
Your Benefits and Compensations All mesothelioma victims may be entitled to social security benefits and compensations from employers or both. These are some of the benefits you might be entitled to: a}Industrial Injuries Disablement Benefit-You can get this quickly paid so you should make your claim as soon as possible so as to be able to get your benefits. b}War disablement pension-If you were exposed to asbestos while serving in the armed forces, you can make this claim from the Veterans Agency. c}Constant Attendance Allowance-This allowance may be paid to you once you receive any of the benefits mentioned above. d}You may also be entitled to a lump sum payment from the Government under the Pneumoconiosis e.t.c{Workers Compensation}Act 1979,or in Northern Ireland,the Pneumoconiosis e.t.c{Workers Compensation}{Northern Ireland}Order 1979.
Whoever you choose to consult about benefits, you should always ask about a payment under the 1979 Act or Order and Industrial Injuries Disablement Benefit.
These and some other benefits and compensations are what you are entitled to if you have been diagnosed with mesothelioma.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com.
If you have worked with asbestos or materials containing asbestos, for example shipyard workers, insulation engineers, maintenance workers, building workers, you can develop mesothelioma. People working in other industries could also be exposed to asbestos without remembering the exposure. Also some people who were exposed to asbestos through washing and handling of clothes contaminated with asbestos and some people living close to asbestos industries may also develop mesothelioma.
Presently there is no known cure for mesothelioma, the treatments available only help to control the symptoms and improve quality of life of the victim. The type of treatment will be individualized and it depends on the stage of the cancer.
Help and Support Every mesothelioma case will need support and help, many find it hard difficult to accept the diagnosis, others feel bitter and angry. Every mesothelioma victim must have access both to information about the disease and to emotional support, including someone to talk to when they feel like. There are several specialist organizations that provide such help.
Your Benefits and Compensations All mesothelioma victims may be entitled to social security benefits and compensations from employers or both. These are some of the benefits you might be entitled to: a}Industrial Injuries Disablement Benefit-You can get this quickly paid so you should make your claim as soon as possible so as to be able to get your benefits. b}War disablement pension-If you were exposed to asbestos while serving in the armed forces, you can make this claim from the Veterans Agency. c}Constant Attendance Allowance-This allowance may be paid to you once you receive any of the benefits mentioned above. d}You may also be entitled to a lump sum payment from the Government under the Pneumoconiosis e.t.c{Workers Compensation}Act 1979,or in Northern Ireland,the Pneumoconiosis e.t.c{Workers Compensation}{Northern Ireland}Order 1979.
Whoever you choose to consult about benefits, you should always ask about a payment under the 1979 Act or Order and Industrial Injuries Disablement Benefit.
These and some other benefits and compensations are what you are entitled to if you have been diagnosed with mesothelioma.
Bello Kamorudeen http://www.mesotheliomacorner.blogspot.com.
Saturday, June 12, 2010
Mesothelioma Blood Test-Mesomark Test
The reason for high death rates among mesothelioma patients is the aggressive nature of the disease and the inability to diagnose it until it is well advanced. Because mesothelioma symptoms do not show up until about 40-50 years after exposure to asbestos, most cases at the time of diagnosis have already reached Stage III or IV. As a result, mesothelioma treatment options are often more palliative than curative.
However, the ability to diagnose the disease at an earlier time would certainly result in a better prognosis for mesothelioma patients. That ability is now present in the form of a mesothelioma blood test known as Mesomark. Developed by Fujirebio Diagnostics Inc. of Malvern, Pennsylvania, a leader in the field of oncology testing, the test measures the amount of a particular biomarker in human serum.
The test was first released in Australia in March 2005 and distribution expanded to Europe just a few months later. Food and Drug Administration approval for the blood test was received nearly two years later in January 2007.
Testing for Mesothelioma
Mesomark is an easily performed blood test that uses an enzyme-linked immunosorbent assay to measure the amount of Soluble Mesothelin-Related Peptides (SMRP) in human serum. SMRP is a biomarker that is produced by mesothelioma cells, and this biomarker may be elevated in the serum of patients who have mesothelioma. The detection of the biomarker through a blood test can help attain an early diagnosis, resulting in more treatment options and a better prognosis for patients.
Mesomark is what is referred to as an in-vitro test. In this test, the blood that is drawn from the patient is sent to a laboratory to measure the level of SMRP. This is performed by using monoclonal antibodies that are known to specifically bind to SMRP. Measuring the amount of bound antibodies in the blood indicates the amount of SMRP, and certain levels indicate the presence of mesothelioma. In addition to detecting the presence of mesothelioma in yet-to-be-diagnosed patients, the Mesomark blood test may also be used to monitor the success of treatments in patients who have already been diagnosed with the disease.
These tests will also help determine the next course of treatment.
The Mesomark blood test has NOT yet been approved for the early diagnosis of mesothelioma.
This test has been approved as a Humanitarian Use Device (HUD), meaning that physicians must follow certain procedures to qualify their patients for testing. Once the physician is certified, informational brochures will be sent to be distributed to each applicable patient.
Those wishing to take part in Mesomark testing will be asked to provide one or more samples of blood. The blood samples will then be sent to a national reference laboratory for testing. In conjunction with other clinical and laboratory data obtained by your doctor, decisions regarding your treatment and care may be simplified. You may discontinue testing at any time.
The costs associated with the Mesomark blood test may not be covered under health insurance, therefore, you may be required to pay all or part of the costs out of pocket. It is recommended that you check with your insurance carrier to determine whether coverage is available under your policy.
Bello kamorudeen.http://www.mesotheliomacorner.blogspot.com
However, the ability to diagnose the disease at an earlier time would certainly result in a better prognosis for mesothelioma patients. That ability is now present in the form of a mesothelioma blood test known as Mesomark. Developed by Fujirebio Diagnostics Inc. of Malvern, Pennsylvania, a leader in the field of oncology testing, the test measures the amount of a particular biomarker in human serum.
The test was first released in Australia in March 2005 and distribution expanded to Europe just a few months later. Food and Drug Administration approval for the blood test was received nearly two years later in January 2007.
Testing for Mesothelioma
Mesomark is an easily performed blood test that uses an enzyme-linked immunosorbent assay to measure the amount of Soluble Mesothelin-Related Peptides (SMRP) in human serum. SMRP is a biomarker that is produced by mesothelioma cells, and this biomarker may be elevated in the serum of patients who have mesothelioma. The detection of the biomarker through a blood test can help attain an early diagnosis, resulting in more treatment options and a better prognosis for patients.
Mesomark is what is referred to as an in-vitro test. In this test, the blood that is drawn from the patient is sent to a laboratory to measure the level of SMRP. This is performed by using monoclonal antibodies that are known to specifically bind to SMRP. Measuring the amount of bound antibodies in the blood indicates the amount of SMRP, and certain levels indicate the presence of mesothelioma. In addition to detecting the presence of mesothelioma in yet-to-be-diagnosed patients, the Mesomark blood test may also be used to monitor the success of treatments in patients who have already been diagnosed with the disease.
These tests will also help determine the next course of treatment.
The Mesomark blood test has NOT yet been approved for the early diagnosis of mesothelioma.
This test has been approved as a Humanitarian Use Device (HUD), meaning that physicians must follow certain procedures to qualify their patients for testing. Once the physician is certified, informational brochures will be sent to be distributed to each applicable patient.
Those wishing to take part in Mesomark testing will be asked to provide one or more samples of blood. The blood samples will then be sent to a national reference laboratory for testing. In conjunction with other clinical and laboratory data obtained by your doctor, decisions regarding your treatment and care may be simplified. You may discontinue testing at any time.
The costs associated with the Mesomark blood test may not be covered under health insurance, therefore, you may be required to pay all or part of the costs out of pocket. It is recommended that you check with your insurance carrier to determine whether coverage is available under your policy.
Bello kamorudeen.http://www.mesotheliomacorner.blogspot.com
Mesothelioma Blood Test-Mesomark Test
The reason for high death rates among mesothelioma patients is the aggressive nature of the disease and the inability to diagnose it until it is well advanced. Because mesothelioma symptoms do not show up until about 40-50 years after exposure to asbestos, most cases at the time of diagnosis have already reached Stage III or IV. As a result, mesothelioma treatment options are often more palliative than curative.
However, the ability to diagnose the disease at an earlier time would certainly result in a better prognosis for mesothelioma patients. That ability is now present in the form of a mesothelioma blood test known as Mesomark. Developed by Fujirebio Diagnostics Inc. of Malvern, Pennsylvania, a leader in the field of oncology testing, the test measures the amount of a particular biomarker in human serum.
The test was first released in Australia in March 2005 and distribution expanded to Europe just a few months later. Food and Drug Administration approval for the blood test was received nearly two years later in January 2007.
Testing for Mesothelioma
Mesomark is an easily performed blood test that uses an enzyme-linked immunosorbent assay to measure the amount of Soluble Mesothelin-Related Peptides (SMRP) in human serum. SMRP is a biomarker that is produced by mesothelioma cells, and this biomarker may be elevated in the serum of patients who have mesothelioma. The detection of the biomarker through a blood test can help attain an early diagnosis, resulting in more treatment options and a better prognosis for patients.
Mesomark is what is referred to as an in-vitro test. In this test, the blood that is drawn from the patient is sent to a laboratory to measure the level of SMRP. This is performed by using monoclonal antibodies that are known to specifically bind to SMRP. Measuring the amount of bound antibodies in the blood indicates the amount of SMRP, and certain levels indicate the presence of mesothelioma. In addition to detecting the presence of mesothelioma in yet-to-be-diagnosed patients, the Mesomark blood test may also be used to monitor the success of treatments in patients who have already been diagnosed with the disease.
These tests will also help determine the next course of treatment.
The Mesomark blood test has NOT yet been approved for the early diagnosis of mesothelioma.
This test has been approved as a Humanitarian Use Device (HUD), meaning that physicians must follow certain procedures to qualify their patients for testing. Once the physician is certified, informational brochures will be sent to be distributed to each applicable patient.
Those wishing to take part in Mesomark testing will be asked to provide one or more samples of blood. The blood samples will then be sent to a national reference laboratory for testing. In conjunction with other clinical and laboratory data obtained by your doctor, decisions regarding your treatment and care may be simplified. You may discontinue testing at any time.
The costs associated with the Mesomark blood test may not be covered under health insurance, therefore, you may be required to pay all or part of the costs out of pocket. It is recommended that you check with your insurance carrier to determine whether coverage is available under your policy.
Bello kamorudeen.http://www.mesotheliomacorner.blogspot.com
However, the ability to diagnose the disease at an earlier time would certainly result in a better prognosis for mesothelioma patients. That ability is now present in the form of a mesothelioma blood test known as Mesomark. Developed by Fujirebio Diagnostics Inc. of Malvern, Pennsylvania, a leader in the field of oncology testing, the test measures the amount of a particular biomarker in human serum.
The test was first released in Australia in March 2005 and distribution expanded to Europe just a few months later. Food and Drug Administration approval for the blood test was received nearly two years later in January 2007.
Testing for Mesothelioma
Mesomark is an easily performed blood test that uses an enzyme-linked immunosorbent assay to measure the amount of Soluble Mesothelin-Related Peptides (SMRP) in human serum. SMRP is a biomarker that is produced by mesothelioma cells, and this biomarker may be elevated in the serum of patients who have mesothelioma. The detection of the biomarker through a blood test can help attain an early diagnosis, resulting in more treatment options and a better prognosis for patients.
Mesomark is what is referred to as an in-vitro test. In this test, the blood that is drawn from the patient is sent to a laboratory to measure the level of SMRP. This is performed by using monoclonal antibodies that are known to specifically bind to SMRP. Measuring the amount of bound antibodies in the blood indicates the amount of SMRP, and certain levels indicate the presence of mesothelioma. In addition to detecting the presence of mesothelioma in yet-to-be-diagnosed patients, the Mesomark blood test may also be used to monitor the success of treatments in patients who have already been diagnosed with the disease.
These tests will also help determine the next course of treatment.
The Mesomark blood test has NOT yet been approved for the early diagnosis of mesothelioma.
This test has been approved as a Humanitarian Use Device (HUD), meaning that physicians must follow certain procedures to qualify their patients for testing. Once the physician is certified, informational brochures will be sent to be distributed to each applicable patient.
Those wishing to take part in Mesomark testing will be asked to provide one or more samples of blood. The blood samples will then be sent to a national reference laboratory for testing. In conjunction with other clinical and laboratory data obtained by your doctor, decisions regarding your treatment and care may be simplified. You may discontinue testing at any time.
The costs associated with the Mesomark blood test may not be covered under health insurance, therefore, you may be required to pay all or part of the costs out of pocket. It is recommended that you check with your insurance carrier to determine whether coverage is available under your policy.
Bello kamorudeen.http://www.mesotheliomacorner.blogspot.com
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