Friday, April 30, 2010

Two Important Steps That Will Help You to Cope With a Diagnosis of Mesothelioma

Receiving a diagnosis of mesothelioma is undoubtedly one of the most devastating and harrowing experiences one can pass through in life, it is like receiving a certain death sentence. All patients will pass through the classical stages of grief, the initial shock followed by denial, then anger, then depression, and finally acceptance of the grim reality of the terminal disease.

This mix of powerful emotions can overwhelm even those that claim to be very strong individuals. This disease often leaves its victims in a very fragile state of mind.

Even the most compassionate and understanding people can be frustrated by the mortality of mesothelioma, and they can become worn out emotionally very quickly if they do not take steps to help them cope with the disease. Mesothelioma diagnosis is a tragic and devastating revelation, and these are some steps that you can take to help you cope with the disease.

1-Try and overcome the fear and sorrow that usually comes with the diagnosis of a terminal illness. Reach out to your friends, strengthen your religious faith, locate and interact with other victims of the disease to learn how they are coping and share experiences with each other. Also draw strength from within your innate powerful resources that can only manifest when you are facing an almost impossible situation like this.

Face this certain mortality with dignity and poise. Fear and hopelessness will only rob you of what little time you have left, and hinder any positive decisions you might have to make.

2-You still control your life, make a choice to make a difference. Try and pursue legal action against those who knowingly put you at risk of developing this cancer, they purposefully exposed you to asbestos exposure to maximize profit and they must pay for their actions. This will serve justice to a callous and very selfish industry.

Also the monetary compensation you will get will give you the assurance that even after you might have passed away, your family will not have to suffer financially. This will also help you to face inevitable mortality with a lot of courage. So contact a mesothelioma Lawyer as soon as possible.

Bello Kamorudeen.

Monday, April 26, 2010

Mesothelioma Chemotherapy - What Are the Six Commonly Used Chemotherapy Agents?

Mesothelioma cancer, can be treated by the use of anti cancer drug therapies. These anti cancer drugs act by inhibiting tumor growth through the blocking of cell division and multiplication. This mode of action also unfortunately affects other rapidly replicating cells in the body, cells of the hair and the lining of the intestine are particularly vulnerable, thus leading to the common side effects of anti cancer drugs like hair loss and nausea.

Mesothelioma is notoriously resistant to common anti cancer chemotherapy as result of some reasons. The cancer takes a long time to mature and show symptoms, by the time these symptoms appear the tumor will be well formed with a lot of layers of dead cells that the anti cancer drugs will find it difficult to penetrate, and also by the time a diagnosis of mesothelioma is made, most victims have but a short time left to live so the drugs do not have enough time to exert their maximal effect.

New drugs that have been designed to overcome these challenges and have fewer and lesser side effects include:

Alimta (Pemetrexed)

Alimta was approved by The Food and Drug Administration in February 2004 as a new anti cancer drug for the treatment of mesothelioma. Its mode of action is by inhibiting the creation of thymidine and purine , two enzymes that are vital to cell growth. This stops the mesothelioma cancer cells from multiplying at a very fast rate. Its side effects include nausea and vomiting, diarrhea, fatigue, mouth sores and low blood counts. Patients are usually placed on vitamin B12 and folic acid supplements to reduce the severity of the side effects.


This is a platinum-based chemotherapy drug that prevents the reproduction of DNA and is used to treat a number of different cancers including mesothelioma. The FDA approved it in 1978 to treat a number of cancers, and has proved somewhat effective on mesothelioma. Cisplatin however has some very serious side effects which inlude ear damage{ototoxicity} leading to hearing loss, kidney damage, nerve damage, and nausea, and so some oncologist are very reluctant to prescribe this drug to patients.

Tomudex (Raltitrexed)

This drug prevents cancer cells from replicating the DNA that is needed for multiplication and spread of cancer. This drug can be used as a monotherapy or in combination with onconase.


This anticancer drug was initially approved by the FDA in 1994 for the treatment of small lung cancer and breast cancer, but recent studies have shown that it could also be effective against mesothelioma, and the drug has little side effect profile. It can also be used in combination with some other chemotherapy drugs.

Onconase (Ranpirnase/P-30 Protein)

Onconase is a chemical taken from the eggs of the leopard frog that blocks protein synthesis which leads to blockage of tumor cell division and growth. It has shown promise as becoming one of the more effective drugs for treating cancer, as survival rates for one and two years are 34.4% and 21.6 respectively, as opposed to six to eight months without treatment.


This is an anticancer chemotherapy drug that blocks the growth of tumors in people suffering from lymphoma, Kaposi's sarcoma, and colon and lung cancers. Many oncologists believe that it could be effective in fighting mesothelioma, as Veglin inhibits vascular endothelial growth factor (VEGF), a substance that is usually found in very high concentrations in mesothelioma patients. VEGF helps tumors grow new blood vessels which help to supply nutrients to the new tumor cells. This drug inhibits this process thus starving the new cancer cells of their much needed nutrients, leading to their ultimate death

Bello Kamorudeen.

Thursday, April 22, 2010

Mesothelioma Chemotherapy - 5 Commonly Asked Mesothelioma Chemotherapy Questions

Mesothelioma patients usually have some questions that they want answers for when they want to commence on Chemotherapy. These include:

1. What is chemotherapy for mesothelioma? Chemotherapy involves one or more anti-cancer drugs taken either orally in pill form, or intravenously, or, in the case of pleural mesothelioma, injected directly into the lungs. These drugs inhibit the growth of cancerous cells, but they also damage normal healthy cells as well leading to the development of side effects.

2. What are the common side effects of mesothelioma chemotherapy? Side effects are very common with the use of many Chemotherapy agents. The commonly seen side effects include:

* hair loss * nausea * vomiting * diarrhea * constipation * anemia * hemorrhaging

Chemotherapy also causes many complicated side effects within the cancerous growth. It is not uncommon in mesothelioma cases to have secondary neoplasms, which are cancerous offshoots of the original tumor that have redirected their growth due to the introduction of anti-cancer drugs.

3. What are the other risks of chemotherapy? Furthermore, chemotherapy often increases the chances of toxic reactions in the blood, liver, and kidneys, contributing to the potential fatal nature of chemotherapy treatment. Because chemotherapy suppresses the immune system by decreasing antibodies in the bloodstream, patients undergoing chemotherapy are vulnerable to having common infections and illnesses. Other complications are mouth sores which, in combination with the overwhelming nausea and intestinal discomfort caused by chemotherapy, results in many patients failing to eat a healthy diet.

4. What can you do if chemotherapy does not work? If you suffer from mesothelioma and chemotherapy has failed you, then you should consult with an attorney experienced in handling asbestos-related litigation. You have a right to pursue legal action to seek justice from those who wronged you. Don't delay, for the laws in your state limit the amount of time you have to collect damages, and these statutes of limitations can end your case before it can begin. Contact a lawyer today.

5. Does chemotherapy work well on mesothelioma? Chemotherapy does not result in a cure for mesothelioma as the cancer is usually too advanced at the time of diagnosis. Newer chemotherapy agents however are very useful in providing symptomatic relief and prolonging the life span of patients especially when used in combination with other modalities of treatment like surgery and radiotherapy.

Bello Kamorudeen.

Sunday, April 18, 2010

mation and copyright must be included. Pleural Mesothelioma Facts

Mesothelioma is the commonest primary tumor of the pleura. There are two main types; 1] the localized mesothelioma{bening and malignant types} 2] the diffuse malignant mesothelioma

Causes There is a strong correlation between asbestos exposure and the development of mesothelioma, although a history of exposure is not always obtainable in patients who have mesothelioma. There are 2 types of asbestos fibres based on crystalline structure; a-serpentine {chrysolite} and b-amphibole. Included within the amphibole are amosite, tremolte, crocidolite and anthophyllite. The most harmful is the crocidolite or better known as blue asbestos.

Localised Bening Mesothelioma

These characteristically arise from the inner layer of the pleura Symptoms and signs; -chest pain -shortness of breath -most of the times there are no symptoms {asymptomatic}, these tumors are usually discovered on routine chest x-ray -hypoglycaemia {low blood sugar} is sometimes associated

Treatment Surgery is the main stay of treatment, the tumor is removed by the surgeon and reccurence is rare and when it happens transition to malignant form of tumor should be suspected.

Localised Malignant Mesothelioma Symptoms and Signs; -chest pain -cough -fever -shortness of breath Treatment Surgery is also the treatment of choice, although prognosis is very poor

Diffuse Malignant Mesothelioma This type of mesothelioma can arise form any part of the pleura and often extend into the peritoneum as well as into the ribs and chest wall {peritoneal mesothelioma and pericardial mesothelioma}. It also spreads commonly to the liver, brain and adrenal glands. Histologically malignant mesothelioma have both fibrous {sarcomatous mesothelioma} and epithelial {papillary} components.

Investigations -CT scan of the chest is extremely useful in diagnosing the extent of the tumor. -Needle biopsy {the surgeon inserts a special needle into the pleura to take samples of the tumor which is taken to the laboratory to see under the microscope} of the pleura is a must. -Pleural fluid is aspirated and taken to the lab for microsopic examination. Staging of Malignant Pleural Mesothelioma -Stage 1:Involvement of ipsilateral pleura and lungs {affecting just one lung either left or right lung} -Stage 2-Invlovement of chest wall, mediastinum {structure at the middle of the heart}, pericardium or contralateral {opposite side} pleura -Stage 3-Distant blood spread into other organs eg brain, adrenals

Treatment Treatment is discouragingly ineffective and survival rarely longer than 2 years with an average of 10-14 months. In selected cases with stage 1 a radical surgery-pleuropneumonectomy may be effective, but long term survival is rare. Primary radiation therapy may be used also. Combination chemotherapy using either single agent or combination protocols have also been used but the outcome remains dismal.

Bello kamorudeen.

Wednesday, April 14, 2010

Mesothelioma - Types and Symptoms

Mesothelioma is a type of cancer that is most commonly caused by an exposure to asbestos. However, mesothelioma symptoms do not show up for many decades after the asbestos exposure. There are mainly three types of mesothelioma: Pleural, peritoneal, and pericardial, and all of them have terrible effects on the victim and their family.

Mesothelioma is not a common form of cancer and it is also the most deadly of all diseases related to asbestos exposure. Keep in mind that just because it is uncommon, it is not considered a rare type of cancer. Because the symptoms mesothelioma exhibits are not very unique as they also tend to show up in other diseases, it is often difficult to diagnose. Treatment may no longer be effective by the time a diagnosis is made. It is one of the least responsive cancers to treatment.

Pleural mesothelioma affects the chest and lungs of its victim. From the chest and lungs, it spreads to different organs in the body, including the brain. Pleural mesothelioma is often not easy to detect. Survival rates are usually about a year and a half from the onset of their symptoms. A very small percentage may survive three to five years.

Pleural mesothelioma symptoms include: * Pain in a specific area of the chest that doesn't seem to go away. * Shortness of breath or breathing problems due to fluid buildup in the chest. * Weight loss * Fever * Aneamia{low blood levels} * Fatigue * Coughing up blood * Jaundice * Low blood sugar * Blood clots * Tumor masses

Peritoneal mesothelioma affects the abdomen and many times spreads to nearby organs, such as the spleen, liver, or bowels. The survival rate is very low, with most patients surviving about ten months after the development of symptoms.

Common peritoneal mesothelioma symptoms include: * Severe abdominal pain * Excessive fluid in the abdomen area * Difficult bowel movements * Nausea and vomiting * Fever * Swollen feet

Pericardial mesothelioma affects the heart and is the least common of the mesothelioma-related cancers. This type of cancer invades the pericardium, the sac surrounding the heart. When the disease progresses, the heart is unable to deliver the right amount of oxygen to the rest of the body. The health of the victim declines very rapidly during the progression of the disease. The most common symptoms resemble a heart attack, with nausea, difficulty in breathing, and pain in the chest.

Mesothelioma treatment is with surgery, chemotherapy and radiation, though there are some experimental treatments are currently been tried for the disease is still in their earlier stages. This serious disease affects more than just the victim; it affects their loved ones as well. As the effects of the disease is devastating, a lot of effort and hard work needs to be done to protect the rights of working men and women.

Bello kamorudeen.

Saturday, April 10, 2010

Mesothelioma Cancer Info

The endothelial lining of blood vessels, lymphatics spaces and serous membranes occasionally give rise to tumors which could be malignant.

They could arise from the pleura (Pleural mesothelioma) and rarely from the pericardium (Pericardial Mesothelioma) or Peritoneum (Peritoneal Mesothelioma.) Asbestos inhalation may provoke their development, blue asbestos fibers especially have been shown to be a cause this.

Pleural Mesothelioma The pleura is often secondarily affected by breast cancer or lung cancer, however Pleural Mesothelioma is one malignant tumor that deserves mention because of the severe nature of the disease and also because of financial compensation the victim is entitled to in most cases.

Pleural Mesothelioma is an aggressive tumor that is associated with asbestos exposure and it is a notifiable condition because the sufferers may be eligible for compensation.

Signs and Symptoms of Pleural Mesothelioma -Unilateral (one sided) pleural effusion (fluid in the pleura) -Shortness of breath -Chest pain -Weight loss in advanced cases -Fever and night sweats in advanced cases

Diagnosis -CT scan shows pleural thickening with compression of the lung. -Thorascopic biopsy (surgeon makes a hole in the chest to get to the pleura and takes sample for laboratory tests)

Treatment of Pleural Mesothelioma The disease follows a progressive course over 12-24 months. Cure is rarely possible because the tumor is unresponsive to radiotherapy or chemotherapy and palliation is difficult, relief and supportive measures are best arranged at an early stage mainly just to prolong if possible, the life of the victim. New forms of treatment have started to emerge, but the results have not been well proven.

Bello kamorudeen.

Tuesday, April 6, 2010

Mesothelioma Attorney - How You Can Find a Good One

If you have been diagnosed with mesothelioma, you have probably been exposed to asbestos before and you have the right to seek for compensation legally. Mesothelioma is a deadly disease caused most of the time by asbestos, a natural mineral used in industries. Mesothelioma affects mainly the pleura (covering of the lungs,) the peritoneum (covering of the abdomen,) and the pericardium (covering of the heart).

Cement companies, shipyards and so many other companies make use of asbestos. To get compensated well by these companies you will need the services of a good mesothelioma attorney to represent you very well. When you begin to search for a good attorney there are certain things you must put into consideration, these include:

-Your attorneys must be legally registered by the government to practice, and they should have a wealth of experience in the issue. Your attorney must have handled similar cases before and won and your lawyers must be able to show you evidence of actually having such experience. To most lawyers it is just business as usual and you need to know that you stand a chance of winning the case. Mesothelioma attorney will be paid when the case is over and they commonly take 40% of the compensation. It is advisable to have agreed with your lawyer on the terms and mode of payment before the case commence.

Some lawyers advertise themselves all over the entire country wishing to get clients from all over, they are usually too expensive and too hectic for most people. Look for a lawyer near or within your state, this will make planning for meetings and court appearances easier. Your lawyer should be able to give you the information on the case in a simple and convincing way, and you should be able to see in them, an understanding and good knowledge of what they are saying. Find out about the background of your lawyers and come up with information with which you will be able to determine their level of competence.

-Your attorney should be positive and should not impose things on you. They should offer advise which you can accept or reject as the might be wrong on some issues and you must decide on certain things pertaining to the case so as to keep a balance of opinions .After you are satisfied with your choice of lawyers, you will need to concentrate on the case, cases like this usually take along time to conclude and you must be determined to fight till the end. When at the end of the case when you win you will be glad that you took you time to find a good mesothelioma attorney.

A good mesothelioma attorney should be positive and should not impose things on you. They need to offer advice and you must have the freedom to refuse it or take it. This is because they might also be wrong and for the purpose of keeping a balance of opinions, you must decide on certain things pertaining to the case. When you are satisfied with your layer, you can then concentrate on the case. It may take a very long time including years to be concluded and you must be prepared to fight through to the end. There is no doubt that after you have won the case, you will look back and appreciate taking the time to find a good lawyer.

Bello kamorudeen

Friday, April 2, 2010

Mesothelioma Cancer Facts

Mesothelioma is a type of cancer that occurs more often among elderly men. The cancer is caused from the effects of exposure to asbestos which affects the membranes of our vital organs such as the heart and lungs. Mesothelioma cancer is not easily diagnosed due to the fact that the symptoms this type of cancer presents are very similar to other diseases such as pneumonia that are much more common.

Pleural Mesothelioma

Pleural Mesothelioma is the commonest form of this disease and accounts for around 75% of all cases of this disease. This type of cancer (Pleural Mesothelioma) attacks and affects the lining of the lungs and presents common symptoms such as difficulty in breathing, coughing and wheezing, chest pains, difficulty in swallowing and in advanced cases, weight loss and fever. These symptoms are very common to other diseases but anyone who has any of them should consult their doctor right away just to be on the safe side especially if they have been exposed to asbestos in the past.

Peritoneal Mesothelioma

Peritoneal Mesothelioma is a less common form of mesothelioma and this type of cancer affects the abdomen. Peritoneal mesothelioma affects the peritoneum{ abdominal lining} and frequently found in people who have been exposed to asbestos and accounts for around 20% of all Mesothelioma cases. Symptoms of Peritoneal Mesothelioma are as follows: abdominal pains, abdominal swelling,weight loss, loss of appetite, weakness and nausea.

The importance of early diagnosis

People who have worked with asbestos or have been exposed to the substance are at risk of developing the disease. One of the most important things that we should remember when dealing with this cancer is that the earlier it is detected the better the outcome so prompt action is needed. Early diagnosis of the disease is of utmost importance so that it can be treated quickly. With time been of importance when dealing with Mesothelioma, the earlier it is discovered the more chance we have of success in its treatment.

Bello kamorudeen.